General control non-repressible 5 (GCN5)-related N-acetyltransferases (GNAT) catalyze the
transfer of an acyl moiety from acyl coenzyme A (acyl-CoA) to a diverse group of substrates …

Glycoconjugates are important mediators of host-pathogen interactions and are usually very
abundant in the surface of many protozoan parasites. However, in the particular case of …

The glycosome of the pathogenic African trypanosome Trypanosoma brucei is a specialized
peroxisome that contains most of the enzymes of glycolysis and several other metabolic and …

Peroxisomes are single-membrane cellular organelles, present in most eukaryotic cells and
organisms from human to yeast, fulfilling essential metabolic functions in lipid metabolism …

Arylalkylamine N-acetyltransferase (aaNAT) catalyzes the transacetylation from acetyl-CoA
to arylalkylamines. aaNATs are involved in sclerotization and neurotransmitter inactivation in …

There is an urgent need to develop new treatments for Chagas' disease. To identify drug
targets, it is important to understand the basic biology of Trypanosoma cruzi, in particular …

Glycosomes are peroxisome-related organelles found in all kinetoplastid protists, including
the human pathogenic species of the family Trypanosomatidae: Trypanosoma brucei …

Leishmania parasites replicate within the phagolysosome compartment of mammalian
macrophages. Although Leishmania depend on sugars as a major carbon source during …

Animals with exoskeleton need to molt to grow and develop. Molting is well described in
some arthropods especially insects. Chitin is a polymer of N-acetylglucosamine, and one of …

The obligate intracellular lifestyle of Plasmodium falciparum and the difficulties in obtaining
sufficient amounts of biological material have hampered the study of specific metabolic …