Abstract Noonan syndrome [NS; Mendelian Inheritance in Men (MIM)# 163950] and related
syndromes [Noonan syndrome with multiple lentigines (formerly called LEOPARD …

Neurofibromatosis type 1 is a rare neurogenetic syndrome, characterized by pigmentary
abnormalities, learning and social deficits, and a predisposition for benign and malignant …

The mushroom body is required for a variety of behaviors of Drosophila melanogaster.
Different types of intrinsic and extrinsic mushroom body neurons might underlie its functional …

Individuals with neurofibromatosis type 1 (NF1) develop abnormalities of both neuronal and
glial cell lineages, suggesting that the NF1 protein neurofibromin is an essential regulator of …

RASopathies are developmental disorders caused by germline mutations in the Ras-MAPK
pathway, and are characterized by a broad spectrum of functional and morphological …

Sleep behavior is conserved throughout evolution, and sleep disturbances are a frequent
comorbidity of neuropsychiatric disorders. However, the molecular basis underlying sleep …

Abstract Neurofibromatosis type 1 (NF1) is a common neurodevelopmental disorder in
which affected individuals are prone to learning, attention and behavioral problems …

Anaplastic Lymphoma Kinase (Alk) is a Receptor Tyrosine Kinase (RTK) activated in several
cancers, but with largely unknown physiological functions. We report two unexpected roles …

Tyrosine phosphorylation plays a significant role in a wide range of cellular processes. The
Drosophila genome encodes more than 20 receptor tyrosine kinases and extensive studies …

Summary Neurofibromatosis type 1 (NF1) is a common autosomal-dominant disorder
associated with attention deficits and learning disabilities. The primary known function of …