Cannabis and adolescent brain development

DI Lubman, A Cheetham, M Yücel - Pharmacology & therapeutics, 2015 - Elsevier
Heavy cannabis use has been frequently associated with increased rates of mental illness
and cognitive impairment, particularly amongst adolescent users. However, the …

Biphasic effects of THC in memory and cognition

EJ Calabrese, A Rubio‐Casillas - European journal of clinical …, 2018 - Wiley Online Library
A generally undesired effect of cannabis smoking is a reversible disruption of short‐term
memory induced by delta‐9‐tetrahydrocannabinol (THC), the primary psychoactive …

Arsenic alters nitric oxide signaling similar to autism spectrum disorder and Alzheimer's disease-associated mutations

MK Tripathi, M Kartawy, S Ginzburg, H Amal - Translational Psychiatry, 2022 - nature.com
Epidemiological studies have proven that exposure to Arsenic (AS) leads to the
development of many neurological disorders. However, few studies have investigated its …

Reversal of age-related cognitive impairments in mice by an extremely low dose of tetrahydrocannabinol

Y Sarne, R Toledano, L Rachmany, E Sasson… - Neurobiology of …, 2018 - Elsevier
This study was designed to test our hypothesis that an ultra-low dose of delta-9
tetrahydrocannabinol (THC) reverses age-dependent cognitive impairments in old mice and …

The dual neuroprotective–neurotoxic profile of cannabinoid drugs

Y Sarne, F Asaf, M Fishbein, M Gafni… - British journal of …, 2011 - Wiley Online Library
Extensive in vitro and in vivo studies have shown that cannabinoid drugs have
neuroprotective properties and suggested that the endocannabinoid system may be …

Cognitive abnormalities and cannabis use

N Solowij, N Pesa - Brazilian Journal of Psychiatry, 2010 - SciELO Brasil
Objective: Evidence that cannabis use impairs cognitive function in humans has been
accumulating in recent decades. The purpose of this overview is to update knowledge in this …

Withdrawal from THC during adolescence: sex differences in locomotor activity and anxiety

LC Harte-Hargrove, DL Dow-Edwards - Behavioural brain research, 2012 - Elsevier
Research suggests that the use and abuse of marijuana can be especially harmful if it
occurs during adolescence, a period of vast developmental changes throughout the brain …

Aging circadian rhythms and cannabinoids

EL Hodges, NM Ashpole - Neurobiology of aging, 2019 - Elsevier
Numerous aspects of mammalian physiology exhibit cyclic daily patterns known as circadian
rhythms. However, studies in aged humans and animals indicate that these physiological …

Behavioral aspects and neurobiological properties underlying medical cannabis treatment in Shank3 mouse model of autism spectrum disorder

S Poleg, E Kourieh, A Ruban, G Shapira… - Translational …, 2021 - nature.com
Autism spectrum disorder (ASD) is a neurodevelopmental disease with a wide spectrum of
manifestation. The core symptoms of ASD are persistent deficits in social communication …

The appetitively motivated “cognitive” holeboard: a family of complex spatial discrimination tasks for assessing learning and memory

FJ van der Staay, ET Gieling, NE Pinzón… - Neuroscience & …, 2012 - Elsevier
Spatial learning and memory tasks have captured a solid position in neuroscience research.
A variety of holeboard-type tasks are suitable for investigating the effects of a broad range of …