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[HTML][HTML] Amino Acid-Based Boron Carriers in Boron Neutron Capture Therapy (BNCT)
J Järvinen, H Pulkkinen, J Rautio, JM Timonen - Pharmaceutics, 2023 - mdpi.com
Interest in the design of boronated amino acids has emerged, partly due to the utilization of
boronophenylalanine (BPA), one of the two agents employed in clinical Boron Neutron …
boronophenylalanine (BPA), one of the two agents employed in clinical Boron Neutron …
4-Borono-2-18F-fluoro-l-phenylalanine PET for boron neutron capture therapy-oriented diagnosis: overview of a quarter century of research
K Ishiwata - Annals of nuclear medicine, 2019 - Springer
10 B-Borono-2-18 F-fluoro-l-phenylalanine (18 F-FBPA) was developed for monitoring the
pharmacokinetics of 4-10 B-borono-l-phenylalanine (10 B-BPA) used in boron neutron …
pharmacokinetics of 4-10 B-borono-l-phenylalanine (10 B-BPA) used in boron neutron …
Poly(vinyl alcohol) boosting therapeutic potential of p-boronophenylalanine in neutron capture therapy by modulating metabolism
T Nomoto, Y Inoue, Y Yao, M Suzuki, K Kanamori… - Science …, 2020 - science.org
In the current clinical boron neutron capture therapy (BNCT), p-boronophenylalanine (BPA)
has been the most powerful drug owing to its ability to accumulate selectively within cancers …
has been the most powerful drug owing to its ability to accumulate selectively within cancers …
[HTML][HTML] Investigation of the impact of L-phenylalanine and L-tyrosine pre-treatment on the uptake of 4-borono-L-phenylalanine in cancerous and normal cells using an …
E Balcer, J Giebułtowicz, M Sochacka, A Ruszczyńska… - Molecules, 2023 - mdpi.com
Boron has gained significant attention in medical research due to its B-10 isotope's high
cross section for the reaction with thermal neutrons, generating ionizing particles that can …
cross section for the reaction with thermal neutrons, generating ionizing particles that can …
Microdistribution and quantification of the boron neutron capture therapy drug BPA in primary cell cultures of human glioblastoma tumour by NanoSIMS
The ability of secondary ion mass spectrometry (SIMS) to provide high sensitivity imaging of
elements and small-medium mass molecules in biological tissues and cells, makes it a very …
elements and small-medium mass molecules in biological tissues and cells, makes it a very …
Preclinical evaluation of new α-radionuclide therapy targeting LAT1: 2-[211At] astato-α-methyl-L-phenylalanine in tumor-bearing model
Y Ohshima, H Suzuki, H Hanaoka, I Sasaki… - Nuclear Medicine and …, 2020 - Elsevier
Introduction Targeted α-radionuclide therapy has attracted attention as a promising therapy
for refractory cancers. However, the application is limited to certain types of cancer. Since L …
for refractory cancers. However, the application is limited to certain types of cancer. Since L …
Influence of fluorine substituents on the properties of phenylboronic compounds
JT Gozdalik, A Adamczyk-Woźniak… - Pure and Applied …, 2018 - degruyter.com
Rapid development of research on the chemistry of boronic acids is connected with their
applications in organic synthesis, analytical chemistry, materials' chemistry, biology and …
applications in organic synthesis, analytical chemistry, materials' chemistry, biology and …
Reliable radiosynthesis of 4-[10B]borono-2-[18F]fluoro-l-phenylalanine with quality assurance for boron neutron capture therapy-oriented diagnosis
K Ishiwata, R Ebinuma, C Watanabe, K Hayashi… - Annals of Nuclear …, 2018 - Springer
Objective The aim of this study was to establish a reliable and routine method for the
preparation of 4-[10 B] borono-2-[18 F] fluoro-l-phenylalanine (l-[18 F] FBPA) for boron …
preparation of 4-[10 B] borono-2-[18 F] fluoro-l-phenylalanine (l-[18 F] FBPA) for boron …
[PDF][PDF] Ruszczy nska, A.; Muszy nska, M.; Bulska, E. Investigation of the Impact of L-Phenylalanine and L-Tyrosine Pre-Treatment on the Uptake of 4-Borono-L …
E Balcer, J Giebułtowicz, M Sochacka - Molecules, 2023 - ppm.wum.edu.pl
Boron has gained significant attention in medical research due to its B-10 isotope's high
cross section for the reaction with thermal neutrons, generating ionizing particles that can …
cross section for the reaction with thermal neutrons, generating ionizing particles that can …
[HTML][HTML] Does Trans-Stimulation of L-Tyrosine Lead to an Increase in Boron Uptake in Head and Neck Squamous Cell Carcinoma Cells?
(1) Background: For advanced head and neck squamous cell carcinoma (HNSCC), boron
neutron capture therapy (BNCT) is a potential therapeutic option, but high concentrations of …
neutron capture therapy (BNCT) is a potential therapeutic option, but high concentrations of …