Emerging micro-and nanotechnology based synthetic approaches for insulin delivery

R Mo, T Jiang, J Di, W Tai, Z Gu - Chemical society reviews, 2014 - pubs.rsc.org
Insulin is essential for type 1 and advanced type 2 diabetics to maintain blood glucose levels
and prolong lives. The traditional administration requires frequent subcutaneous insulin …

Potential of insulin nanoparticle formulations for oral delivery and diabetes treatment

CY Wong, H Al-Salami, CR Dass - Journal of controlled release, 2017 - Elsevier
Nanoparticles have demonstrated significant advancements in potential oral delivery of
insulin. In this publication, we review the current status of polymeric, inorganic and solid-lipid …

Regulation of the renal NaCl cotransporter and its role in potassium homeostasis

EJ Hoorn, M Gritter, CA Cuevas… - Physiological …, 2020 - journals.physiology.org
Daily dietary potassium (K+) intake may be as large as the extracellular K+ pool. To avoid
acute hyperkalemia, rapid removal of K+ from the extracellular space is essential. This is …

Obesity, insulin resistance, diabetes, and cardiovascular risk in children: an American Heart Association scientific statement from the Atherosclerosis, Hypertension …

J Steinberger, SR Daniels - Circulation, 2003 - Am Heart Assoc
Atherosclerotic cardiovascular disease is the No. 1 killer in the adult population of Western
societies, 1 but the pathological processes and risk factors associated with its development …

Relation of weight and rate of increase in weight during childhood and adolescence to body size, blood pressure, fasting insulin, and lipids in young adults: the …

AR Sinaiko, RP Donahue, DR Jacobs Jr, RJ Prineas - Circulation, 1999 - Am Heart Assoc
Background—Weight gain is of concern during early development because adult obesity
and its cardiovascular consequences appear to have their origins during childhood. Insulin …

Obesity-induced hypertension. Renal function and systemic hemodynamics.

JE Hall, MW Brands, WN Dixon, MJ Smith Jr - Hypertension, 1993 - Am Heart Assoc
This study examined the control of renal hemodynamics and tubular function, as well as
systemic hemodynamics, during obesity-induced hypertension in chronically instrumented …

[PDF][PDF] Hypertension and obesity

A Aneja, F El-Atat, SI McFarlane… - Recent progress in …, 2004 - endocrine.org
Obesity is a common problem in much of the western world today in that is linked directly
with several disease processes, notably, hypertension. It is becoming clear that the …

Visceral adiposity is an independent predictor of incident hypertension in Japanese Americans

T Hayashi, EJ Boyko, DL Leonetti… - Annals of internal …, 2004 - acpjournals.org
Background: Visceral adiposity is generally considered to play a key role in the metabolic
syndrome. Objective: To examine the relationship between directly measured visceral …

A randomized trial of rosiglitazone therapy in patients with inadequately controlled insulin-treated type 2 diabetes

P Raskin, M Rendell, MC Riddle, JF Dole… - Diabetes …, 2001 - Am Diabetes Assoc
OBJECTIVE—To determine the efficacy and safety of rosiglitazone (RSG) when added to
insulin in the treatment of type 2 diabetic patients who are inadequately controlled on insulin …

Louis K. Dahl Memorial Lecture. Renal and cardiovascular mechanisms of hypertension in obesity.

JE Hall - Hypertension, 1994 - Am Heart Assoc
In all forms of hypertension, including human essential hypertension, pressure natriuresis is
reset to higher blood pressures. Because human essential hypertension is a heterogeneous …