Effects of disturbed flow on vascular endothelium: pathophysiological basis and clinical perspectives

JJ Chiu, S Chien - Physiological reviews, 2011 - journals.physiology.org
Vascular endothelial cells (ECs) are exposed to hemodynamic forces, which modulate EC
functions and vascular biology/pathobiology in health and disease. The flow patterns and …

CFD: computational fluid dynamics or confounding factor dissemination? The role of hemodynamics in intracranial aneurysm rupture risk assessment

J **ang, VM Tutino, KV Snyder… - American Journal of …, 2014 - Am Soc Neuroradiology
Image-based computational fluid dynamics holds a prominent position in the evaluation of
intracranial aneurysms, especially as a promising tool to stratify rupture risk. Current …

Image-based modeling of blood flow and vessel wall dynamics: applications, methods and future directions: Sixth International Bio-Fluid Mechanics Symposium and …

CA Taylor, DA Steinman - Annals of biomedical engineering, 2010 - Springer
The objective of our session at the 2008 International Bio-Fluid Symposium and Workshop
was to review the state-of-the-art in image-based modeling of blood flow, and identify future …

Patient-specific multiscale modeling of blood flow for coronary artery bypass graft surgery

S Sankaran, M Esmaily Moghadam, AM Kahn… - Annals of biomedical …, 2012 - Springer
We present a computational framework for multiscale modeling and simulation of blood flow
in coronary artery bypass graft (CABG) patients. Using this framework, only CT and non …

Low wall shear stress is independently associated with the rupture status of middle cerebral artery aneurysms

Y Miura, F Ishida, Y Umeda, H Tanemura, H Suzuki… - Stroke, 2013 - Am Heart Assoc
Background and Purpose—We determined which hemodynamic parameter independently
characterizes the rupture status of middle cerebral artery (MCA) aneurysms using …

Association of hemodynamic factors with intracranial aneurysm formation and rupture: systematic review and meta-analysis

A Can, R Du - Neurosurgery, 2016 - journals.lww.com
BACKGROUND: Recent evidence suggests a link between the magnitude and distribution of
hemodynamic factors and the formation and rupture of intracranial aneurysms. However …

CFD for evaluation and treatment planning of aneurysms: review of proposed clinical uses and their challenges

B Chung, JR Cebral - Annals of biomedical engineering, 2015 - Springer
Computational fluid dynamics (CFD) has been used for several years to identify mechanical
risk factors associated with aneurysmal evolution and rupture as well as to understand flow …

Hemodynamics of cerebral aneurysm initiation: the role of wall shear stress and spatial wall shear stress gradient

Z Kulcsár, A Ugron, M Marosfői… - American Journal …, 2011 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: Cerebral aneurysms are preferentially located at arterial
curvatures and bifurcations that are exposed to major hemodynamic forces, increasingly …

Suggested connections between risk factors of intracranial aneurysms: a review

JR Cebral, M Raschi - Annals of biomedical engineering, 2013 - Springer
The purpose of this article is to review studies of aneurysm risk factors and the suggested
hypotheses that connect the different risk factors and the underlying mechanisms governing …

Characterizations and correlations of wall shear stress in aneurysmal flow

A Arzani, SC Shadden - Journal of biomechanical …, 2016 - asmedigitalcollection.asme.org
Wall shear stress (WSS) is one of the most studied hemodynamic parameters, used in
correlating blood flow to various diseases. The pulsatile nature of blood flow, along with the …