Current concepts in the pathophysiology and treatment of aplastic anemia

NS Young, RT Calado, P Scheinberg - Blood, 2006 - ashpublications.org
Aplastic anemia, an unusual hematologic disease, is the paradigm of the human bone
marrow failure syndromes. Almost universally fatal just a few decades ago, aplastic anemia …

Aplastic anemia

NS Young, P Scheinberg… - Current opinion in …, 2008 - journals.lww.com
Evidence has accumulated in the recent years further corroborating an immune-mediated
process underlying aplastic anemia pathogenesis. Hematopoietic stem-cell transplantation …

Aplastic anaemia

RA Brodsky, RJ Jones - The Lancet, 2005 - thelancet.com
Aplastic anaemia is a rare haemopoietic stem-cell disorder that results in pancytopenia and
hypocellular bone marrow. Although most cases are acquired, there are unusual inherited …

Diagnosis and treatment of aplastic anemia

SA Peslak, T Olson, DV Babushok - Current treatment options in oncology, 2017 - Springer
Opinion statement Acquired aplastic anemia (AA) is a rare, life-threatening bone marrow
failure (BMF) disorder that affects patients of all ages and is caused by lymphocyte …

Aplastic anaemia: Current concepts in diagnosis and management

E Furlong, T Carter - Journal of paediatrics and child health, 2020 - Wiley Online Library
Aplastic anaemia is a rare, previously fatal condition with a significantly improved survival
rate owing to advances in understanding of the pathophysiology and improved treatment …

Acquired aplastic anemia in children

HD Hartung, TS Olson, M Bessler - Pediatric Clinics, 2013 - pediatric.theclinics.com
Acquired aplastic anemia (AA) in childhood remains an uncommon, life-threatening
disorder. Because of major advances in diagnosis and therapeutic approaches, AA in …

Diagnosis and management of acquired aplastic anemia in childhood. Guidelines from the Marrow Failure Study Group of the Pediatric Haemato-Oncology Italian …

A Barone, A Lucarelli, D Onofrillo, F Verzegnassi… - Blood Cells, Molecules …, 2015 - Elsevier
Acquired aplastic anemia (AA) is a rare heterogeneous disease characterized by
pancytopenia and hypoplastic bone marrow. The incidence is 2–3/million inhabitants/year …

An update on the management of severe idiopathic aplastic anaemia in children

JK Davies, EC Guinan - British journal of haematology, 2007 - Wiley Online Library
The current outlook for a child with severe idiopathic aplastic anaemia (AA) is very much
better than in previous decades. In part, this may reflect better differentiation of idiopathic …

Eltrombopag for patients with moderate aplastic anemia or uni-lineage cytopenias

X Fan, R Desmond, T Winkler, DJ Young… - Blood …, 2020 - ashpublications.org
There is no standard or widely effective treatment of patients with moderate aplastic anemia
(MAA) or hypo-productive uni-lineage cytopenias (UC). Eltrombopag (EPAG), a small …

Quantitative analysis of bone marrow CD34 cells in aplastic anemia and hypoplastic myelodysplastic syndromes

WH Matsui, RA Brodsky, BD Smith, MJ Borowitz… - Leukemia, 2006 - nature.com
Aplastic anemia (AA) and hypoplastic myelodysplastic syndromes (hMDS) are often difficult
to distinguish. However, an accurate diagnosis is important because the prognosis and …