Background Monocytes and macrophages are essential components of innate immune
system and have versatile roles in homeostasis and immunity. These phenotypically …

Ulcerative colitis (UC), a type of inflammatory bowel disease characterized by recurring and
incurable symptoms, causes immense suffering and economic burden for patients due to the …

Rationale: Ulcerative colitis (UC), a typical kind of inflammatory bowel disease (IBD), is an
idiopathic chronic intestinal inflammation. Conventional therapeutic strategies mainly focus …

Inflammatory bowel disease (IBD) is one of the main factors leading to colitis-associated
colorectal cancer (CAC). Therefore, it is critical to develop an effective treatment for IBD to …

Inflammatory bowel disease (IBD) has been closely associated with immune disorders and
excessive M1 macrophage activation, which can be reversed by the M2-polarizing effect of …

Patients with inflammatory bowel disease (IBD) have increased incidence of colorectal
cancer (CRC). IBD-associated cancer follows a well-characterized sequence of intestinal …

Inflammatory response by different polarized macrophages has a critical role in a variety of
immunological pathophysiology, such as ulcerative colitis (UC). Herein, targeting the …

Background Inflammation and oxidative stress play an important role in the pathophysiology
of inflammatory bowel disease (IBD). This study aimed to explore the effects of copper …

Objectives Cognitive dysfunction has been identified as a major symptom of a series of
psychiatric disorders. Multidisciplinary studies have shown that cognitive dysfunction is …

Inflammatory bowel disease (IBD) is associated with acute and chronic inflammation of the
gastrointestinal tract and has emerged to be a global disease. Spermidine, a natural …