Molecular evolution tracks macroevolutionary transitions in Cetacea

MR McGowen, J Gatesy, DE Wildman - Trends in ecology & evolution, 2014 - cell.com
Cetacea (whales, dolphins, and porpoises) is a model group for investigating the molecular
signature of macroevolutionary transitions. Recent research has begun to reveal the …

Genes lost during the transition from land to water in cetaceans highlight genomic changes associated with aquatic adaptations

M Huelsmann, N Hecker, MS Springer, J Gatesy… - Science …, 2019 - science.org
The transition from land to water in whales and dolphins (cetaceans) was accompanied by
remarkable adaptations. To reveal genomic changes that occurred during this transition, we …

Diving deep: understanding the genetic components of hypoxia tolerance in marine mammals

AG Hindle - Journal of Applied Physiology, 2020 - journals.physiology.org
Marine mammals have highly specialized physiology, exhibited in many species by extreme
breath-holding capabilities that allow deep dives and extended submergence …

Evolutionary genetics of hypoxia tolerance in cetaceans during diving

R Tian, Z Wang, X Niu, K Zhou, S Xu… - Genome biology and …, 2016 - academic.oup.com
Hypoxia was a major challenge faced by cetaceans during the course of secondary aquatic
adaptation. Although physiological traits of hypoxia tolerance in cetaceans have been well …

'Obesity'is healthy for cetaceans? Evidence from pervasive positive selection in genes related to triacylglycerol metabolism

Z Wang, Z Chen, S Xu, W Ren, K Zhou, G Yang - Scientific reports, 2015 - nature.com
Cetaceans are a group of secondarily adapted marine mammals with an enigmatic history of
transition from terrestrial to fully aquatic habitat and subsequent adaptive radiation in waters …

Genomic evidence for sensorial adaptations to a nocturnal predatory lifestyle in owls

P Espíndola-Hernández, JC Mueller… - Genome biology and …, 2020 - academic.oup.com
Owls (Strigiformes) evolved specific adaptations to their nocturnal predatory lifestyle, such
as asymmetrical ears, a facial disk, and a feather structure allowing silent flight. Owls also …

Myoglobin oxygen affinity in aquatic and terrestrial birds and mammals

TJ Wright, RW Davis - The Journal of experimental biology, 2015 - journals.biologists.com
Myoglobin (Mb) is an oxygen binding protein found in vertebrate skeletal muscle, where it
facilitates intracellular transport and storage of oxygen. This protein has evolved to suit …

Dolphin leukocytes exhibit an attenuated cytokine response and increase heme oxygenase activity upon exposure to lipopolysaccharides

CA Reyes-Ramos, LJ Ramírez-Jirano… - … and Physiology Part A …, 2023 - Elsevier
Cetaceans exhibit physiological adaptations that allowed the transition to aquatic life,
including a robust antioxidant defense system that prevents injury from repeated exposure to …

Tracing whale myoglobin evolution by resurrecting ancient proteins

Y Isogai, H Imamura, S Nakae, T Sumi, K Takahashi… - Scientific reports, 2018 - nature.com
Extant cetaceans, such as sperm whale, acquired the great ability to dive into the ocean
depths during the evolution from their terrestrial ancestor that lived about 50 million years …

Common and unique strategies of myoglobin evolution for deep-sea adaptation of diving mammals

Y Isogai, H Imamura, S Nakae, T Sumi, K Takahashi… - Iscience, 2021 - cell.com
Myoglobin (Mb) is highly concentrated in the myocytes of diving mammals such as whales
and seals, in comparison with land animals, and its molecular evolution has played a crucial …