Molecular mechanisms and physiological importance of circadian rhythms

A Patke, MW Young, S Axelrod - Nature reviews Molecular cell biology, 2020 - nature.com
To accommodate daily recurring environmental changes, animals show cyclic variations in
behaviour and physiology, which include prominent behavioural states such as sleep–wake …

Associations between REV-ERBα, sleep duration and body mass index in European adolescents

MVN Ferreira, L Goumidi, HB Carvalho… - Sleep medicine, 2018 - Elsevier
Abstract Background/Objective Although the REV-ERBα is considered an important
regulator of both clock function and metabolism, its relationship with sleep duration and …

Regulation of exercise ability and glycolipid metabolism by synthetic SR9009 analogues as new REV-ERB-α agonists

L Li, C Yang, X Qiao, X Yang, J Zhang, M Cui… - Bioorganic & Medicinal …, 2024 - Elsevier
SR9009 is an activator of REV-ERBs with diverse biological activities, including improving
exercise tolerance and controlling skeletal muscle mass. To optimise the carbamate motif of …

Rev-erbα regulates hepatic ischemia-reperfusion injury in mice

Y Lin, L Lin, L Gao, S Wang, B Wu - Biochemical and Biophysical Research …, 2020 - Elsevier
Hepatic ischemia-reperfusion (I/R) injury is a complex pathophysiological process that often
times occurs in liver transplantation, hepatectomy, and ischemic shock. Aberrant activation …

REV-ERBα agonist SR9009 promotes a negative energy balance in goldfish

N Saiz, L Herrera-Castillo, E Isorna… - International Journal of …, 2022 - mdpi.com
REV-ERBα (nr1d1, nuclear receptor subfamily 1 group D member 1) is a transcriptional
repressor that in mammals regulates nutrient metabolism, and has effects on energy …

[PDF][PDF] Rev-erbα circadian rhythms: putative role on food intake and metabolism in goldfish

A Cebrián, N Saiz, M Gómez-Boronat… - … presented at the XII …, 2021 - scholar.archive.org
In this work we explore the role of the nuclear receptor REV-ERBα as a link in the
crosstalking between the circadian system and the energy homeostasis in goldfish …