Chemotherapy—induced gastrointestinal dysfunction is a common occurrence associated
with many different classes of chemotherapeutic agents. Gastrointestinal toxicity includes …

The gastrointestinal tract is particularly vulnerable to off-target effects of antineoplastic drugs
because intestinal epithelial cells proliferate rapidly and have a complex immunological …

The characteristic hypoxia of solid tumors and inadequate oxygen supply become a key
causation of the resistance to chemotherapy in cancer treatment. Herein, a bimetallic oxygen …

Doxorubicin is an effective anti-neoplastic agent; the reported toxicities of DOX limit its use.
Luteolin is a polyphenolic phytochemical that exhibits beneficial biological effects via …

This study aimed to develop an efficient step-by-step osteosarcoma (OS)-targeting liposome
system functionalized with a redox-cleavable, bone-and cluster of differentiation 44 (CD44) …

Background Cardiovascular disease (CVD) is a significant worldwide factor contributing to
human fatality and morbidity. With the increase of incidence rates, it is of concern that there …

Background and Aims P-Coumaric acid (PCA) is one the compound that has free radical
scavenging effects. This study investigates the protective effect of PCA on tissue damage in …

Nicorandil ameliorated doxorubicin-induced nephrotoxicity; this study aimed to show and
explain the mechanism of this protection. A precise method was elucidated to study the …

Doxorubicin (DOX), is a drug against lung malignancies with undesirable side effect
including oxidative, inflammatory and apoptotic effects. Luteolin (LUT), present in fruits and …

Disruption of the alveolar–endothelial barrier caused by inflammation leads to the
progression of septic acute lung injury (ALI). In the present study, we investigated the …