Retinal neurodegeneration is predominantly reported as the apoptosis or impaired function
of the photoreceptors. Retinal degeneration is a major causative factor of irreversible vision …

The eye is an immune privileged tissue that insulates the visual system from local and
systemic immune provocation to preserve homeostatic functions of highly specialized retinal …

Purpose To analyze the factors associated with response (control of ocular inflammation and
corticosteroid-sparing effect) to biologics (anti–tumor necrosis factor [TNF]-α agents and …

Purpose: Geographic atrophy (GA) is a clinical phenotype of late age-related macular
degeneration (AMD) with no current treatment available. In this study, we investigated …

The intestinal tract is densely populated by microbiota consisting of various commensal
microorganisms that are instrumental for the healthy state of the living organism. Such …

Increasing evidence suggests that chronic inflammation plays an important role in the
pathogenesis of age-related macular degeneration (AMD); however, the precise pathogenic …

Adenosine is an endogenous purine nucleoside ubiquitously distributed throughout the
body that interacts with G protein-coupled receptors, classified in four subtypes: A 1 R, A 2A …

The purpose of this study is evaluate the efficacy and safety of medicinal products containing
the original Age-Related Eye Disease group (AREDS) formulation at doses approved in …

Inflammation plays a crucial role in the etiology and pathogenesis of AMD (Age-related
Macular Degeneration). Humanin G (HNG) is a Mitochondrial Derived Peptide (MDP) that is …

This review article delves into the intricate roles of reactive oxygen species (ROS) in the
pathogenesis of age-related macular degeneration (AMD). It presents a detailed analysis of …