Phospholipid ether (PLE) CAR T cell tumor targeting (CTCT) agents

MC Jensen, J Matthaei - US Patent 11,649,288, 2023 - Google Patents
TZCPCKNHXULUIY-RGULYWFUSA-N 1, 2-distearoyl-sn-glycero-3-phosphoserine
Chemical compound CCCCCCCCCCCCCCCCCC (= O) OC [C@ H](COP (O)(= O) OC [C …

Methods of use for CAR T cells

MC Jensen, J Matthaei - US Patent 11,311,576, 2022 - Google Patents
The present disclosure relates to methods of treating a patient with a cancer by
administering to the patient a composition comprising CAR T cells wherein the CAR T cells …

Methods and compositions for car t cell therapy

PS Low, CHU Haiyan, YG Lee - US Patent 12,144,850, 2024 - Google Patents
The present disclosure relates to methods of treating a patient with a cancer by
administering to the patient a composition comprising CAR T cells and a small molecule …

Methods of use for CAR T cells

PS Low, CHU Haiyan, YJ Lu, CP Leamon… - US Patent …, 2023 - Google Patents
The present disclosure relates to methods of treating a patient with a cancer by
administering to the patient a composition comprising CAR T cells wherein the CAR T cells …

Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics

PS Low, CHU Haiyan, YG Lee - US Patent App. 17/387,892, 2022 - Google Patents
(57) ABSTRACT Related US Application Data (63) Continuation of application No.
15/296,666, filed on Oct. 18, 2016, now abandoned, which is a continu ation of application …

Chimeric antigen receptor system with adaptable receptor specificity

JM Carton, MF Naso, LG Borges, J Wheeler… - US Patent …, 2024 - Google Patents
YOHYSYJDKVYCJI-UHFFFAOYSA-N n-[3-[[6-[3-(trifluoromethyl) anilino] pyrimidin-4-yl]
amino] phenyl] cyclopropanecarboxamide Chemical compound FC (F)(F) C1= CC= CC …

Compositions and methods for CAR T cell therapy

PS Low, CHU Haiyan, YG Lee, CP Leamon… - US Patent …, 2023 - Google Patents
The present disclosure relates to methods of treating a patient with a cancer by
administering to the patient a composition comprising CAR T cells and a small molecule …

Anti-mesothelin antigen-binding molecules and uses thereof

C Correnti, C Mehlin, D Meininger… - US Patent …, 2024 - Google Patents
The present disclosure provides antibodies and polypeptides that specifically bind to
mesothelin (MSLN), including bispecific antibodies that bind both MSLN and a T cell antigen …

Immune cells having co-expressed shRNAS and logic gate systems

J Williams, M Nguyen, A Yao, S Santoro… - US Patent …, 2024 - Google Patents
2023-08-08 Assigned to ARSENAL BIOSCIENCES, INC. reassignment ARSENAL
BIOSCIENCES, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR …

Compositions and methods for car t cell therapy

PS Low, CHU Haiyan, YG Lee, CP Leamon… - US Patent …, 2023 - Google Patents
The present disclosure relates to methods of treating a patient with a cancer by
administering to the patient a composition comprising CAR T cells and a small molecule …