Quinones as neuroprotective agents
Á Cores, N Carmona-Zafra, J Clerigué, M Villacampa… - Antioxidants, 2023 - mdpi.com
Quinones can in principle be viewed as a double-edged sword in the treatment of
neurodegenerative diseases, since they are often cytoprotective but can also be cytotoxic …
neurodegenerative diseases, since they are often cytoprotective but can also be cytotoxic …
Attenuation of Nrf2/Keap1/ARE in Alzheimer's disease by plant secondary metabolites: A mechanistic review
Alzheimer's disease (AD) is a progressive neuronal/cognitional dysfunction, leading to
disability and death. Despite advances in revealing the pathophysiological mechanisms …
disability and death. Despite advances in revealing the pathophysiological mechanisms …
Apelin-13 suppresses neuroinflammation against cognitive deficit in a streptozotocin-induced rat model of Alzheimer's disease through activation of BDNF-TrkB …
H Luo, Y **ang, X Qu, H Liu, C Liu, G Li… - Frontiers in …, 2019 - frontiersin.org
Alzheimer's disease (AD), a progressive neurodegenerative disease characterized by
impairments of cognitive function as a result of synaptic deficits and neuronal loss, is …
impairments of cognitive function as a result of synaptic deficits and neuronal loss, is …
Rutin improves anxiety and reserpine-induced depression in rats
Mental disorders have a poor clinical prognosis and account for approximately 8% of the
global burden of disease. Some examples of mental disorders are anxiety and depression …
global burden of disease. Some examples of mental disorders are anxiety and depression …
Design, synthesis, and pharmacological evaluation of embelin–aryl/alkyl amine hybrids as orally bioavailable blood–brain barrier permeable multitargeted agents with …
VK Nuthakki, S Choudhary, CN Reddy… - ACS chemical …, 2023 - ACS Publications
The complex and multifaceted nature of Alzheimer's disease has brought about a pressing
demand to develop ligands targeting multiple pathways to combat its outrageous …
demand to develop ligands targeting multiple pathways to combat its outrageous …
[HTML][HTML] Sterubin protects against chemically-induced Alzheimer's disease by reducing biomarkers of inflammation-IL-6/IL-β/TNF-α and oxidative stress-SOD/MDA in …
Sterubin, a flavanone is an active chemical compound that possesses neuroprotective
activity. The current investigation was intended to assess the sterubin effect in scopolamine …
activity. The current investigation was intended to assess the sterubin effect in scopolamine …
Rosmarinus officinalis and Mentha piperita Oils Supplementation Enhances Memory in a Rat Model of Scopolamine-Induced Alzheimer's Disease-like Condition
Alzheimer's disease is regarded as a common neurodegenerative disease that may lead to
dementia and the loss of memory. We report here the nootropic and anti-amnesic effects of …
dementia and the loss of memory. We report here the nootropic and anti-amnesic effects of …
HMGB1/RAGE/TLR4 axis and glutamate as novel targets for PCSK9 inhibitor in high fat cholesterol diet induced cognitive impairment and amyloidosis
Aims Alzheimer's disease (AD) is a leading health problem in which increased amyloid β
(Aβ) accumulation may occur due to abnormal Aβ precursor protein processing by β …
(Aβ) accumulation may occur due to abnormal Aβ precursor protein processing by β …
Insight into the emerging and common experimental in-vivo models of Alzheimer's disease
R Dhapola, S Kumari, P Sharma… - Laboratory Animal …, 2023 - Springer
Alzheimer's disease (AD) is a multifactorial, rapidly progressing neurodegenerative disorder.
As the exact cause of the disease is still unclear, the drug development is very challenging …
As the exact cause of the disease is still unclear, the drug development is very challenging …
Anticholinergic effect of resveratrol with vitamin E on scopolamine-induced Alzheimer's disease in rats: Mechanistic approach to prevent inflammation
The most common form of dementia, Alzheimer's disease (AD), is characterized by gradual
declines in cognitive abilities and behavior. It is caused by a combination of factors …
declines in cognitive abilities and behavior. It is caused by a combination of factors …