[HTML][HTML] Changes in intestinal tight junction permeability associated with industrial food additives explain the rising incidence of autoimmune disease

A Lerner, T Matthias - Autoimmunity reviews, 2015 - Elsevier
The incidence of autoimmune diseases is increasing along with the expansion of industrial
food processing and food additive consumption. The intestinal epithelial barrier, with its …

Site-specific antibody drug conjugates for cancer therapy

S Panowski, S Bhakta, H Raab, P Polakis, JR Junutula - MAbs, 2014 - Taylor & Francis
Antibody therapeutics have revolutionized the treatment of cancer over the past two
decades. Antibodies that specifically bind tumor surface antigens can be effective …

Action of microbial transglutaminase (MTGase) in the modification of food proteins: A review

ALC Gaspar, SP de Góes-Favoni - Food chemistry, 2015 - Elsevier
Microbial transglutaminase (MTGase) is an enzyme of the class of transferases widely
known to modify protein functional properties in food systems. The main mechanisms of …

Microbial transglutaminase and its application in the food industry. A review

M Kieliszek, A Misiewicz - Folia microbiologica, 2014 - Springer
The extremely high costs of manufacturing transglutaminase from animal origin (EC 2.3.
2.13) have prompted scientists to search for new sources of this enzyme. Interdisciplinary …

Location matters: site of conjugation modulates stability and pharmacokinetics of antibody drug conjugates

P Strop, SH Liu, M Dorywalska, K Delaria, RG Dushin… - Chemistry & biology, 2013 - cell.com
Antibody drug conjugates (ADCs) are a therapeutic class offering promise for cancer
therapy. The attachment of cytotoxic drugs to antibodies can result in an effective therapy …

Antibody-drug conjugates for cancer therapy: chemistry to clinical implications

N Dan, S Setua, VK Kashyap, S Khan, M Jaggi… - Pharmaceuticals, 2018 - mdpi.com
Chemotherapy is one of the major therapeutic options for cancer treatment. Chemotherapy
is often associated with a low therapeutic window due to its poor specificity towards tumor …

Antibody–drug conjugates as novel anti-cancer chemotherapeutics

C Peters, S Brown - Bioscience reports, 2015 - portlandpress.com
Over the past couple of decades, antibody–drug conjugates (ADCs) have revolutionized the
field of cancer chemotherapy. Unlike conventional treatments that damage healthy tissues …

Modification methods and applications of egg protein gel properties: A review

X Lv, X Huang, B Ma, Y Chen, Z Batool… - … Reviews in Food …, 2022 - Wiley Online Library
Egg protein (EP) has a variety of functional properties, such as gelling, foaming, and
emulsifying. The gel characteristics provide a foundation for applications in the food industry …

Celiac disease: from pathogenesis to novel therapies

D Schuppan, Y Junker, D Barisani - Gastroenterology, 2009 - Elsevier
Celiac disease has become one of the best-understood HLA-linked disorders. Although it
shares many immunologic features with inflammatory bowel disease, celiac disease is …

Enzyme-catalyzed protein crosslinking

T Heck, G Faccio, M Richter, L Thöny-Meyer - Applied microbiology and …, 2013 - Springer
The process of protein crosslinking comprises the chemical, enzymatic, or chemoenzymatic
formation of new covalent bonds between polypeptides. This allows (1) the site-directed …