2014 AHA/ACC guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Task …

RA Nishimura, CM Otto, RO Bonow… - Journal of the American …, 2014 - jacc.org
The recommendations listed in this document are, whenever possible, evidence based. An
extensive review was conducted on literature published through November 2012, and other …

Calcific aortic stenosis

BR Lindman, MA Clavel, P Mathieu, B Iung… - Nature reviews Disease …, 2016 - nature.com
Calcific aortic stenosis (AS) is the most prevalent heart valve disorder in developed
countries. It is characterized by progressive fibro-calcific remodelling and thickening of the …

2020 ACC/AHA guideline for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Joint …

Writing Committee Members, CM Otto… - Journal of the American …, 2021 - jacc.org
The recommendations listed in this document are, whenever possible, evidence based. An
extensive review was conducted on literature published through March 1, 2020. Searches …

Aortic-valve stenosis—from patients at risk to severe valve obstruction

CM Otto, B Prendergast - New England Journal of Medicine, 2014 - Mass Medical Soc
Aortic-Valve Stenosis — From Patients at Risk to Severe Valve Obstruction | New England Journal
of Medicine Skip to main content Access provided by Charite - Universitaetsmedizin Berlin The …

Engineered in vitro disease models

KH Benam, S Dauth, B Hassell… - Annual Review of …, 2015 - annualreviews.org
The ultimate goal of most biomedical research is to gain greater insight into mechanisms of
human disease or to develop new and improved therapies or diagnostics. Although great …

Convolutional and recurrent neural networks for the detection of valvular heart diseases in phonocardiogram recordings

M Alkhodari, L Fraiwan - Computer Methods and Programs in Biomedicine, 2021 - Elsevier
Valvular heart diseases (VHD) are one of the major causes of cardiovascular diseases that
are having high mortality rates worldwide. The early diagnosis of VHD prevents the …

Elevated lipoprotein (a) and risk of aortic valve stenosis in the general population

PR Kamstrup, A Tybjærg-Hansen… - Journal of the American …, 2014 - jacc.org
Objectives: The purpose of this study was to determine whether elevated lipoprotein (a)
levels and corresponding LPA risk genotypes (rs10455872, rs3798220, kringle IV type 2 …

Calcific aortic valve disease: mechanisms, prevention and treatment

LHM Moncla, M Briend, Y Bossé… - Nature Reviews Cardiology, 2023 - nature.com
Calcific aortic valve disease (CAVD) is the most common disorder affecting heart valves and
is characterized by thickening, fibrosis and mineralization of the aortic valve leaflets …

Calcification in aortic stenosis: the skeleton key

TA Pawade, DE Newby, MR Dweck - Journal of the American College of …, 2015 - jacc.org
Aortic stenosis is a common, potentially fatal condition that is set to become an increasing
public health burden. Once symptoms develop, there is an inexorable deterioration with a …

Why and how to measure aortic valve calcification in patients with aortic stenosis

T Pawade, T Sheth, E Guzzetti, MR Dweck… - JACC: Cardiovascular …, 2019 - jacc.org
The first-line evaluation of aortic stenosis severity is Doppler echocardiography. However, in
up to 40% of patients, resting echocardiographic assessment of aortic stenosis severity is …