Production of biopharmaceuticals in E. coli: current scenario and future perspectives
Escherichia coli is the most preferred microorganism to express heterologous proteins for
therapeutic use, as around 30% of the approved therapeutic proteins are currently being …
therapeutic use, as around 30% of the approved therapeutic proteins are currently being …
Recent advances, challenges and metabolic engineering strategies in the biosynthesis of 3‐hydroxypropionic acid
B Liang, G Sun, X Zhang, Q Nie… - Biotechnology and …, 2022 - Wiley Online Library
As an attractive and valuable platform chemical, 3‐hydroxypropionic acid (3‐HP) can be
used to produce a variety of industrially important commodity chemicals and biodegradable …
used to produce a variety of industrially important commodity chemicals and biodegradable …
Production of Rainbow Colorants by Metabolically Engineered Escherichia coli
There has been much interest in producing natural colorants to replace synthetic colorants
of health concerns. Escherichia coli has been employed to produce natural colorants …
of health concerns. Escherichia coli has been employed to produce natural colorants …
High-yield ectoine production in engineered Corynebacterium glutamicum by fine metabolic regulation via plug-in repressor library
A Jiang, Y Song, J You, X Zhang, M Xu, Z Rao - Bioresource Technology, 2022 - Elsevier
Ectoine is a high-value protective and stabilizing agent with different applications in
biopharmaceuticals, biotechnology, and fine chemicals. Here, efficient production of ectoine …
biopharmaceuticals, biotechnology, and fine chemicals. Here, efficient production of ectoine …
Systematic Screening of Optimal Signal Peptides for Secretory Production of Heterologous Proteins in Bacillus subtilis
G Fu, J Liu, J Li, B Zhu, D Zhang - Journal of agricultural and food …, 2018 - ACS Publications
Bacillus subtilis is widely used for large-scale industrial production of heterologous proteins.
Because of its high intrinsic secretory capacity, it can efficiently secrete proteins into the …
Because of its high intrinsic secretory capacity, it can efficiently secrete proteins into the …
Circuit-guided population acclimation of a synthetic microbial consortium for improved biochemical production
Microbial consortia have been considered potential platforms for bioprocessing applications.
However, the complexity in process control owing to the use of multiple strains necessitates …
However, the complexity in process control owing to the use of multiple strains necessitates …
[HTML][HTML] Tools and principles for microbial gene circuit engineering
Synthetic biologists aim to construct novel genetic circuits with useful applications through
rational design and forward engineering. Given the complexity of signal processing that …
rational design and forward engineering. Given the complexity of signal processing that …
Cyanobacterial secondary metabolites towards improved commercial significance through multiomics approaches
Cyanobacteria are ubiquitous photosynthetic prokaryotes responsible for the oxygenation of
the earth's reducing atmosphere. Apart from oxygen they are producers of a myriad of …
the earth's reducing atmosphere. Apart from oxygen they are producers of a myriad of …
Engineering nitrogenases for synthetic nitrogen fixation: from pathway engineering to directed evolution
Globally, agriculture depends on industrial nitrogen fertilizer to improve crop growth.
Fertilizer production consumes fossil fuels and contributes to environmental nitrogen …
Fertilizer production consumes fossil fuels and contributes to environmental nitrogen …
[PDF][PDF] Improving protein production on the level of regulation of both expression and secretion pathways in Bacillus subtilis
The well-characterized gram-positive bacterium Bacillus subtilis is an outstanding industrial
candidate for protein expression owing to its single membrane and high capacity of …
candidate for protein expression owing to its single membrane and high capacity of …