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Conformational transitions and ligand-binding to a muscle-type nicotinic acetylcholine receptor
Fast synaptic communication requires receptors that respond to the presence of
neurotransmitter by opening an ion channel across the post-synaptic membrane. The …
neurotransmitter by opening an ion channel across the post-synaptic membrane. The …
Molecular simulations of hydrophobic gating of pentameric ligand gated ion channels: insights into water and ions
Ion channels are proteins which form gated nanopores in biological membranes. Many
channels exhibit hydrophobic gating, whereby functional closure of a pore occurs by local …
channels exhibit hydrophobic gating, whereby functional closure of a pore occurs by local …