Photoactive ruthenium nitrosyls: Effects of light and potential application as NO donors

MJ Rose, PK Mascharak - Coordination chemistry reviews, 2008 - Elsevier
In recent years, various exogenous nitric oxide (NO) donors have been synthesized to
modulate NO concentrations in cellular environments and control physiological processes …

Biological activity of ruthenium nitrosyl complexes

E Tfouni, DR Truzzi, A Tavares, AJ Gomes… - Nitric oxide, 2012 - Elsevier
Nitric oxide plays an important role in various biological processes, such as
neurotransmission, blood pressure control, immunological responses, and antioxidant …

New features in the redox coordination chemistry of metal nitrosyls {M–NO+; M–NO; M–NO−(HNO)}

F Roncaroli, M Videla, LD Slep, JA Olabe - Coordination Chemistry …, 2007 - Elsevier
We describe new developments in the coordination chemistry of bound nitrosyl, considering
its three formal redox states: NO+, NO and NO−/HNO. We emphasize on the correlation …

Influence of ancillary ligand L in the nitric oxide photorelease by the [Ru (L)(tpy) NO] 3+ complex and its vasodilator activity based on visible light irradiation

RG de Lima, MG Sauaia, D Bonaventura… - Inorganica chimica …, 2006 - Elsevier
The photochemical and pharmacological studies of the novel [Ru (L)(tpy) NO] 3+ L= bpy (2,
2′-bipyridine), NH· NHq (quinonediimine) and NH2. NH2cat (o-phenylenediamine) were …

Development of nitrosyl ruthenium complex-loaded lipid carriers for topical administration: improvement in skin stability and in nitric oxide release by visible light …

F Marquele-Oliveira, DC de Almeida Santana… - … of Pharmaceutical and …, 2010 - Elsevier
The prominent nitric oxide (NO) donor [Ru (terpy)(bdqi) NO](PF6) 3 has been synthesized
and evaluated with respect to noteworthy biological effects due to its NO photorelease …

In vitro and in vivo antiproliferative and trypanocidal activities of ruthenium NO donors

JJN Silva, AL Osakabe, WR Pavanelli… - British journal of …, 2007 - Wiley Online Library
Background and purpose: Many compounds liberating NO (NO donors) have been used as
therapeutic agents. Here we test two ruthenium nitrosyls, which release NO when activated …

Synthesis, spectroscopic analysis and photolabilization of water-soluble ruthenium (III)–nitrosyl complexes

AC Merkle, AB McQuarters, N Lehnert - Dalton Transactions, 2012 - pubs.rsc.org
In this paper, the synthesis, structural and spectroscopic characterization of a series of new
Ru (III)–nitrosyls of {RuNO} 6 type with the coligand TPA (tris (2-pyridylmethyl) amine) are …

Ruthenium phosphine/diimine complexes: Syntheses, characterization, reactivity with carbon monoxide, and catalytic hydrogenation of ketones

MP de Araujo, AT de Figueiredo, AL Bogado… - …, 2005 - ACS Publications
The cis-[RuCl2 (PPh3) 2 (N− N)](N− N= bipy (1), Me-bipy (2), phen (3), and bathophen (4))
complexes were used to synthesize five new electron-rich phosphine-containing complexes …

Antileishmanial activity of ruthenium (II) tetraammine nitrosyl complexes

JCM Pereira, V Carregaro, DL Costa… - European journal of …, 2010 - Elsevier
The complexes trans-[Ru (NO)(NH3) 4L](X) 3 (X= BF4−, PF6− or Cl− and L= N-heterocyclic
ligands, P (OEt) 3, SO3− 2), and [Ru (NO) Hedta)] were shown to exhibit IC50pro in the …

Photoinduced nitric oxide and singlet oxygen release from ZnPC liposome vehicle associated with the nitrosyl ruthenium complex: synergistic effects in photodynamic …

DS Maranho, RG De Lima, FL Primo… - Photochemistry and …, 2009 - Wiley Online Library
Under continuous photolysis at 675 nm, liposomal zinc phthalocyanine associated with
nitrosyl ruthenium complex [Ru (NH. NHq)(tpy) NO] 3+ showed the detection and …