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Perivascular spaces in the brain: anatomy, physiology and pathology
Perivascular spaces include a variety of passageways around arterioles, capillaries and
venules in the brain, along which a range of substances can move. Although perivascular …
venules in the brain, along which a range of substances can move. Although perivascular …
Inflammation and cerebral small vessel disease: a systematic review
Inflammation is increasingly implicated as a risk factor for dementia, stroke, and small vessel
disease (SVD). However, the underlying mechanisms and causative pathways remain …
disease (SVD). However, the underlying mechanisms and causative pathways remain …
The Boston criteria version 2.0 for cerebral amyloid angiopathy: a multicentre, retrospective, MRI–neuropathology diagnostic accuracy study
Background Cerebral amyloid angiopathy (CAA) is an age-related small vessel disease,
characterised pathologically by progressive deposition of amyloid β in the cerebrovascular …
characterised pathologically by progressive deposition of amyloid β in the cerebrovascular …
Clinical significance of magnetic resonance imaging markers of vascular brain injury: a systematic review and meta-analysis
Importance Covert vascular brain injury (VBI) is highly prevalent in community-dwelling
older persons, but its clinical and therapeutic implications are debated. Objective To better …
older persons, but its clinical and therapeutic implications are debated. Objective To better …
Glymphatic system impairment in Alzheimer's disease: associations with perivascular space volume and cognitive function
X Zhang, Y Wang, B Jiao, Z Wang, J Shi, Y Zhang… - European …, 2024 - Springer
Objectives To investigate glymphatic function in Alzheimer's disease (AD) using the diffusion
tensor image analysis along the perivascular space (DTI-ALPS) method and to explore the …
tensor image analysis along the perivascular space (DTI-ALPS) method and to explore the …
Hypertension, neurodegeneration, and cognitive decline
Elevated blood pressure is a well-established risk factor for age-related cognitive decline.
Long linked to cognitive impairment on vascular bases, increasing evidence suggests a …
Long linked to cognitive impairment on vascular bases, increasing evidence suggests a …
Understanding the role of the perivascular space in cerebral small vessel disease
Small vessel diseases (SVDs) are a group of disorders that result from pathological
alteration of the small blood vessels in the brain, including the small arteries, capillaries and …
alteration of the small blood vessels in the brain, including the small arteries, capillaries and …
Update on cerebral small vessel disease: a dynamic whole-brain disease
Y Shi, JM Wardlaw - Stroke and vascular neurology, 2016 - svn.bmj.com
Cerebral small vessel disease (CSVD) is a very common neurological disease in older
people. It causes stroke and dementia, mood disturbance and gait problems. Since it is …
people. It causes stroke and dementia, mood disturbance and gait problems. Since it is …
Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration
Cerebral small vessel disease (SVD) is a common accompaniment of ageing. Features seen
on neuroimaging include recent small subcortical infarcts, lacunes, white matter …
on neuroimaging include recent small subcortical infarcts, lacunes, white matter …
Perivascular spaces, glymphatic dysfunction, and small vessel disease
Cerebral small vessel diseases (SVDs) range broadly in etiology but share remarkably
overlap** pathology. Features of SVD including enlarged perivascular spaces (EPVS) …
overlap** pathology. Features of SVD including enlarged perivascular spaces (EPVS) …