A review on the green synthesis of benzimidazole derivatives and their pharmacological activities

M Nardi, NCH Cano, S Simeonov, R Bence, A Kurutos… - Catalysts, 2023 - mdpi.com
Benzimidazoles and their derivatives play an extraordinarily significant role as therapeutic
agents, eg, antiulcer, analgesic, and anthelmintic drugs. The organic synthesis of …

Deep eutectic solvents as reusable catalysts and promoter for the greener syntheses of small molecules: Recent advances

SE Hooshmand, S Kumar, I Bahadur, T Singh… - Journal of Molecular …, 2023 - Elsevier
Deep eutectic solvents (DESs) are significant environmentally benign media in the field of
green chemistry. They are known not only for their inexpensive nature, biodegradability, non …

Natural deep eutectic solvent as extraction media for the main phenolic compounds from olive oil processing wastes

S Bonacci, ML Di Gioia, P Costanzo, L Maiuolo… - Antioxidants, 2020 - mdpi.com
In this new century, sustainable development challenges chemical sciences to develop new
and clean technological processes. The agri-food industry produces significant quantities of …

A review on synthetic approaches of benzimidazoles

VAS Pardeshi, NS Chundawat, SI Pathan… - Synthetic …, 2021 - Taylor & Francis
From the group of heterocyclic compounds, benzimidazoles remain the central focus, which
owns the important features as six-five member attached rings having two nitrogen atoms at …

[HTML][HTML] Benzimidazole: A Versatile Scaffold for Drug Discovery and Beyond-A Comprehensive Review of Synthetic Approaches and Recent Advancements in …

ND Mahurkar, ND Gawhale, MN Lokhande, SJ Uke… - Results in …, 2023 - Elsevier
Heterocyclic compounds are foundational in drug discovery, constituting the core structure of
approximately 80% of pharmaceuticals. Benzimidazole, in particular, emerges as a critical …

[HTML][HTML] An overview on novel synthetic approaches and medicinal applications of benzimidazole compounds

HE Hashem, Y El Bakri - Arabian Journal of Chemistry, 2021 - Elsevier
Benzimidazole, a benzene-fused heterocyclic compound, has acquired significant attention
in the field of contemporary medicinal chemistry because of its wide array of …

Recent progress in catalytic synthesis of 1, 2, 3-triazoles

A De Nino, L Maiuolo, P Costanzo, V Algieri, A Jiritano… - Catalysts, 2021 - mdpi.com
1, 2, 3-triazoles represent a functional heterocyclic core that has been at the center of
modern organic chemistry since the beginning of click chemistry. Being a versatile …

Deep eutectic solvents for improving the solubilization and delivery of dapsone

S Trombino, C Siciliano, D Procopio, F Curcio… - Pharmaceutics, 2022 - mdpi.com
Owing to a growing awareness toward environmental impact, the use of safer and eco-
friendly solvents like deep eutectic solvents (DESs), has recently undergone important …

Green solvents for the formation of amide linkages

D Procopio, C Siciliano, S Trombino… - Organic & …, 2022 - pubs.rsc.org
The formation of the amide bond is among the most commonly performed transformations in
the pharmaceutical industry and the wider chemical industry. The current methods for its …

A panoramic review of benzimidazole derivatives and their potential biological activity

H Hernández-López… - Mini Reviews in …, 2022 - ingentaconnect.com
The therapeutic potential of the benzimidazole nucleus has been recognized since 1944,
and it is an important heterocycle system due to its presence in a wide range of bioactive …