Mechanisms of drug resistance: quinolone resistance
DC Hooper, GA Jacoby - Annals of the New York academy of …, 2015 - Wiley Online Library
Quinolone antimicrobials are synthetic and widely used in clinical medicine. Resistance
emerged with clinical use and became common in some bacterial pathogens. Mechanisms …
emerged with clinical use and became common in some bacterial pathogens. Mechanisms …
Topoisomerase inhibitors: fluoroquinolone mechanisms of action and resistance
DC Hooper, GA Jacoby - Cold Spring …, 2016 - perspectivesinmedicine.cshlp.org
Quinolone antimicrobials are widely used in clinical medicine and are the only current class
of agents that directly inhibit bacterial DNA synthesis. Quinolones dually target DNA gyrase …
of agents that directly inhibit bacterial DNA synthesis. Quinolones dually target DNA gyrase …
Defining the oral microbiome by whole-genome sequencing and resistome analysis: the complexity of the healthy picture
Background The microbiome of the oral cavity is the second-largest and diverse microbiota
after the gut, harboring over 700 species of bacteria and including also fungi, viruses, and …
after the gut, harboring over 700 species of bacteria and including also fungi, viruses, and …
Acquired antibiotic resistance genes: an overview
AHAM Van Hoek, D Mevius, B Guerra… - Frontiers in …, 2011 - frontiersin.org
In this review an overview is given on antibiotic resistance (AR) mechanisms with special
attentions to the AR genes described so far preceded by a short introduction on the …
attentions to the AR genes described so far preceded by a short introduction on the …
Transforming clinical microbiology with bacterial genome sequencing
Whole-genome sequencing of bacteria has recently emerged as a cost-effective and
convenient approach for addressing many microbiological questions. Here, we review the …
convenient approach for addressing many microbiological questions. Here, we review the …
An evaluation of multidrug-resistant Escherichia coli isolates in urinary tract infections from Aguascalientes, Mexico: cross-sectional study
FY Ramírez-Castillo, AC Moreno-Flores… - Annals of clinical …, 2018 - Springer
Abstract Background Uropathogenic Escherichia coli (UPEC) are one of the main bacteria
causing urinary tract infections (UTIs). The rates of UPEC with high resistance towards …
causing urinary tract infections (UTIs). The rates of UPEC with high resistance towards …
Resistance Plasmid Families in Enterobacteriaceae
A Carattoli - Antimicrobial agents and chemotherapy, 2009 - Am Soc Microbiol
Bacteria carry extrachromosomal, self-replicating genetic elements called plasmids. A
plasmid is defined as a doublestranded, circular DNA molecule capable of autonomous …
plasmid is defined as a doublestranded, circular DNA molecule capable of autonomous …
Plasmid-mediated quinolone resistance: a multifaceted threat
J Strahilevitz, GA Jacoby, DC Hooper… - Clinical microbiology …, 2009 - Am Soc Microbiol
Although plasmid-mediated quinolone resistance (PMQR) was thought not to exist before its
discovery in 1998, the past decade has seen an explosion of research characterizing this …
discovery in 1998, the past decade has seen an explosion of research characterizing this …
Quinolones: from antibiotics to autoinducers
S Heeb, MP Fletcher, SR Chhabra… - FEMS microbiology …, 2011 - academic.oup.com
Since quinine was first isolated, animals, plants and microorganisms producing a wide
variety of quinolone compounds have been discovered, several of which possess …
variety of quinolone compounds have been discovered, several of which possess …
Pyrosequencing of antibiotic-contaminated river sediments reveals high levels of resistance and gene transfer elements
The high and sometimes inappropriate use of antibiotics has accelerated the development
of antibiotic resistance, creating a major challenge for the sustainable treatment of infections …
of antibiotic resistance, creating a major challenge for the sustainable treatment of infections …