In recent years, unique physicochemical properties of amphiphilic block copolymers have
been utilized to design the polymeric micelles for brain-specific delivery of drugs, proteins …

Neurovascular unit (NVU) inflammation via activation of glial cells and neuronal damage
plays a critical role in neurodegenerative diseases. Though the exact mechanism of disease …

Neuropsychiatric disorders including Alzheimer's disease (AD) may cause gut inflammation
and dysbiosis. Gut inflammation-suppressing probiotics alleviate neuropsychiatric disorders …

Cognitive impairment is one of the major symptoms in most neurodegenerative disorders
such as Alzheimer's (AD), Parkinson (PD), and Huntington diseases (HD), affecting millions …

GABAergic inhibitory neurons are the principal source of inhibition in the brain. Traditionally,
their role in maintaining the balance of excitation-inhibition has been emphasized. Beyond …

Alzheimer's disease is widely regarded as poorly treated due to poor conceptualization. For
40 years, Alzheimer's disease pathophysiology has focused on two culprits, amyloid-β …

Abstract Alzheimer's disease (AD), a chronic, progressive, neurodegenerative disorder, is
the most common type of dementia. Beta amyloid (Aβ) peptide aggregation and …

Background As an increasing population of Alzheimer's disease (AD) patients year by year,
which is a serious threat to human health, an effective approach to prevent and treat AD is …

Poor quality and quantity of sleep are very common in elderly people throughout the world.
Growing evidence has suggested that sleep disturbances could accelerate the process of …

Dramatic advancement has been made in recent decades to understand the basis of
autoimmunity-mediated neurological diseases. These diseases create a strong influence on …