Integrin receptors are the main molecular link between cells and the extracellular matrix
(ECM) as well as mediating cell–cell interactions. Integrin–ECM binding triggers the …

In recent decades synthetic polymers have gained increasing popularity, and nowadays
they are an integral part of people's daily lives. In addition, owing to their competitive …

Across complex, multi-time and-length scale biological systems, redundancy confers
robustness and resilience, enabling adaptation and increasing survival under dynamic …

Recent evidence clearly shows that cells respond to various physical cues in their
environments, guiding many cellular processes and tissue morphogenesis, pathology, and …

Cellular form and function emerge from complex mechanochemical systems within the
cytoplasm. Currently, no systematic strategy exists to infer large-scale physical properties of …

Tight coupling between biochemical and mechanical properties of the actin cytoskeleton
drives a large range of cellular processes including polarity establishment, morphogenesis …

Signals from the microenvironment around a cell are known to influence cell behavior.
Material properties, such as biochemical composition and substrate stiffness, are today …

Cellular mechanisms underlying the development of left–right asymmetry in tissues and
embryos remain obscure. Here, the development of a chiral pattern of actomyosin was …

Among the physicochemical cues in the cellular microenvironment that orchestrate cell
processes, the different levels of curvature in the extracellular matrix and intrinsic to the …

Significant efforts have been directed to understanding the factors that influence the lineage
commitment of stem cells. This paper demonstrates that cell shape, independent of soluble …