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Diversity, versatility and complexity of bacterial gene regulation mechanisms: opportunities and drawbacks for applications in synthetic biology
I Bervoets, D Charlier - FEMS microbiology reviews, 2019 - academic.oup.com
Gene expression occurs in two essential steps: transcription and translation. In bacteria, the
two processes are tightly coupled in time and space, and highly regulated. Tight regulation …
two processes are tightly coupled in time and space, and highly regulated. Tight regulation …
Contextualizing context for synthetic biology–identifying causes of failure of synthetic biological systems
S Cardinale, AP Arkin - Biotechnology journal, 2012 - Wiley Online Library
Despite the efforts that bioengineers have exerted in designing and constructing biological
processes that function according to a predetermined set of rules, their operation remains …
processes that function according to a predetermined set of rules, their operation remains …
Synthetic genetic circuits as a means of reprogramming plant roots
The shape of a plant's root system influences its ability to reach essential nutrients in the soil
and to acquire water during drought. Progress in engineering plant roots to optimize water …
and to acquire water during drought. Progress in engineering plant roots to optimize water …
[BUCH][B] The emergence of life: from chemical origins to synthetic biology
PL Luisi - 2016 - books.google.com
Addressing the emergence of life from a systems biology perspective, this new edition has
undergone extensive revision, reflecting changes in scientific understanding and evolution …
undergone extensive revision, reflecting changes in scientific understanding and evolution …
Distributed biological computation with multicellular engineered networks
Ongoing efforts within synthetic and systems biology have been directed towards the
building of artificial computational devices using engineered biological units as basic …
building of artificial computational devices using engineered biological units as basic …
Partitioning of a 2-bit hash function across 66 communicating cells
JP Padmakumar, JJ Sun, W Cho, Y Zhou… - Nature Chemical …, 2024 - nature.com
Powerful distributed computing can be achieved by communicating cells that individually
perform simple operations. Here, we report design software to divide a large genetic circuit …
perform simple operations. Here, we report design software to divide a large genetic circuit …
Towards a rational approach to promoter engineering: understanding the complexity of transcription initiation in prokaryotes
C Deal, L De Wannemaeker… - FEMS Microbiology …, 2024 - academic.oup.com
Promoter sequences are important genetic control elements. Through their interaction with
RNA polymerase they determine transcription strength and specificity, thereby regulating the …
RNA polymerase they determine transcription strength and specificity, thereby regulating the …
Next-generation synthetic gene networks
Synthetic biology is focused on the rational construction of biological systems based on
engineering principles. During the field's first decade of development, significant progress …
engineering principles. During the field's first decade of development, significant progress …
Synthetic in vitro transcriptional oscillators
The construction of synthetic biochemical circuits from simple components illuminates how
complex behaviors can arise in chemistry and builds a foundation for future biological …
complex behaviors can arise in chemistry and builds a foundation for future biological …
Quantitative characterization of genetic parts and circuits for plant synthetic biology
Plant synthetic biology promises immense technological benefits, including the potential
development of a sustainable bio-based economy through the predictive design of synthetic …
development of a sustainable bio-based economy through the predictive design of synthetic …