Short-chain fatty acids in diseases

D Zhang, YP Jian, YN Zhang, Y Li, LT Gu… - Cell Communication and …, 2023 - Springer
Short-chain fatty acids (SCFAs) are the main metabolites produced by bacterial fermentation
of dietary fibre in the gastrointestinal tract. The absorption of SCFAs is mediated by substrate …

The function of gut microbiota in immune-related neurological disorders: A review

P Sittipo, J Choi, S Lee, YK Lee - Journal of neuroinflammation, 2022 - Springer
This review provides an overview of the importance of microbiota in the regulation of gut–
brain communication in immune-related neurological disorders. The gastrointestinal (GI) …

[HTML][HTML] Gut microbiota-derived short-chain fatty acids: impact on cancer treatment response and toxicities

GH Al-Qadami, KR Secombe, CB Subramaniam… - Microorganisms, 2022 - mdpi.com
The gut microbiota has emerged as a key modulator of cancer treatment responses in terms
of both efficacy and toxicity. This effect is clearly mediated by processes impacting the …

[HTML][HTML] Role of microbiota short-chain fatty acids in the pathogenesis of autoimmune diseases

A Rasouli-Saravani, K Jahankhani, S Moradi… - Biomedicine & …, 2023 - Elsevier
There is emerging evidence that microbiota and its metabolites play an important role in
helath and diseases. In this regard, gut microbiota has been found as a crucial component …

Short-chain fatty acids in cancer pathogenesis

MA Feitelson, A Arzumanyan, A Medhat… - Cancer and Metastasis …, 2023 - Springer
Cancer is a multi-step process that can be viewed as a cellular and immunological shift
away from homeostasis in response to selected infectious agents, mutations, diet, and …

[HTML][HTML] The impact of microbiota-derived short-chain fatty acids on macrophage activities in disease: Mechanisms and therapeutic potentials

H Duan, LJ Wang, M Huangfu, H Li - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Short-chain fatty acids (SCFAs) derived from the fermentation of carbohydrates by gut
microbiota play a crucial role in regulating host physiology. Among them, acetate …

[HTML][HTML] Dual role of microbiota-derived short-chain fatty acids on host and pathogen

R Mirzaei, E Dehkhodaie, B Bouzari, M Rahimi… - Biomedicine & …, 2022 - Elsevier
A growing body of documents shows microbiota produce metabolites such as short-chain
fatty acids (SCFAs) as crucial executors of diet-based microbial influence the host and …

Short-chain fatty acids—a product of the microbiome and its participation in two-way communication on the microbiome-host mammal line

O Lange, M Proczko-Stepaniak, A Mika - Current obesity reports, 2023 - Springer
Abstract Purpose of Review The review aims to describe short-chain fatty acids (SCFAs) as
metabolites of bacteria, their complex influence on whole-body metabolism, and alterations …

Microbiome as a biomarker and therapeutic target in pancreatic cancer

G Pourali, D Kazemi, AS Chadeganipour… - BMC microbiology, 2024 - Springer
Studying the effects of the microbiome on the development of different types of cancer has
recently received increasing research attention. In this context, the microbial content of …

[HTML][HTML] Mediterranean diet and olive oil, microbiota, and obesity-related cancers. From mechanisms to prevention

E Almanza-Aguilera, A Cano, M Gil-Lespinard… - Seminars in Cancer …, 2023 - Elsevier
Olive oil (OO) is the main source of added fat in the Mediterranean diet (MD). It is a mix of
bioactive compounds, including monounsaturated fatty acids, phytosterols, simple phenols …