Resolving the prefrontal mechanisms of adaptive cognitive behaviors: A cross-species perspective

IL Hanganu-Opatz, T Klausberger, T Sigurdsson… - Neuron, 2023 - cell.com
The prefrontal cortex (PFC) enables a staggering variety of complex behaviors, such as
planning actions, solving problems, and adapting to new situations according to external …

The generative grammar of the brain: a critique of internally generated representations

G Dragoi - Nature Reviews Neuroscience, 2024 - nature.com
The past decade of progress in neurobiology has uncovered important organizational
principles for network preconfiguration and neuronal selection that suggest a generative …

Nested compressed co-representations of multiple sequential experiences during sleep

K Liu, J Sibille, G Dragoi - Nature Neuroscience, 2024 - nature.com
Animals encounter and remember multiple experiences daily. During sleep, hippocampal
neuronal ensembles replay past experiences and preplay future ones. Although most …

Experience of Euclidean geometry sculpts the development and dynamics of rodent hippocampal sequential cell assemblies

U Farooq, G Dragoi - Nature Communications, 2024 - nature.com
Euclidean space is the fabric of the world we live in. Whether and how geometric experience
shapes our spatial-temporal representations of the world remained unknown. We deprived …

The hippocampal horizon: Constructing and segmenting experience for episodic memory

TW Ross, A Easton - Neuroscience & Biobehavioral Reviews, 2022 - Elsevier
How do we recollect specific events that have occurred during continuous ongoing
experience? There is converging evidence from non-human animals that spatially …

The two tales of hippocampal sharp-wave ripple content: The rigid and the plastic

AF Hall, DV Wang - Progress in neurobiology, 2023 - Elsevier
Sharp-wave ripples, prominently in the CA1 region of the hippocampus, are short oscillatory
events accompanied by bursts of neural firing. Ripples and associated hippocampal place …

Geometric experience sculpts the development and dynamics of hippocampal sequential cell assemblies

U Farooq, G Dragoi - bioRxiv, 2023 - biorxiv.org
Euclidean space is the fabric of the world we live in. Whether and how geometric experience
shapes our spatial-temporal representations of the world remained unknown. We deprived …

Intrinsic dynamics of randomly clustered networks generate place fields and preplay of novel environments

J Breffle, H Germaine, JD Shin, SP Jadhav, P Miller - Elife, 2024 - elifesciences.org
During both sleep and awake immobility, hippocampal place cells reactivate time-
compressed versions of sequences representing recently experienced trajectories in a …

The generalized spatial representation in the prefrontal cortex is inherited from the hippocampus

M Nardin, K Kaefer, J Csicsvari - BioRxiv, 2021 - biorxiv.org
Hippocampal and neocortical neural activity is modulated by the position of the individual in
space. While hippocampal neurons provide the basis for a spatial map, prefrontal cortical …

Leveraging place field repetition to understand positional versus nonpositional inputs to hippocampal field CA1

W Hockeimer, RY Lai, M Natrajan, W Snider… - bioRxiv, 2022 - biorxiv.org
The hippocampus is believed to encode episodic memory by binding information about the
content of experience within a spatiotemporal framework encoding the location and …