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Interpreting artificial intelligence models: a systematic review on the application of LIME and SHAP in Alzheimer's disease detection
Explainable artificial intelligence (XAI) has gained much interest in recent years for its ability
to explain the complex decision-making process of machine learning (ML) and deep …
to explain the complex decision-making process of machine learning (ML) and deep …
Explainable artificial intelligence in Alzheimer's disease classification: A systematic review
The unprecedented growth of computational capabilities in recent years has allowed
Artificial Intelligence (AI) models to be developed for medical applications with remarkable …
Artificial Intelligence (AI) models to be developed for medical applications with remarkable …
[HTML][HTML] Treatment of Alzheimer's disease: beyond symptomatic therapies
FR Buccellato, M D'Anca, GM Tartaglia… - International Journal of …, 2023 - mdpi.com
In an ever-increasing aged world, Alzheimer's disease (AD) represents the first cause of
dementia and one of the first chronic diseases in elderly people. With 55 million people …
dementia and one of the first chronic diseases in elderly people. With 55 million people …
BACE1: More than just a β‐secretase
HA Taylor, L Przemylska, EM Clavane… - Obesity …, 2022 - Wiley Online Library
Summary β‐site amyloid precursor protein cleaving enzyme‐1 (BACE1) research has
historically focused on its actions as the β‐secretase responsible for the production of β …
historically focused on its actions as the β‐secretase responsible for the production of β …
The impact of tau deposition and hypometabolism on cognitive impairment and longitudinal cognitive decline
INTRODUCTION Tau and neurodegeneration strongly correlate with cognitive impairment,
as compared to amyloid. However, their contribution in explaining cognition and predicting …
as compared to amyloid. However, their contribution in explaining cognition and predicting …
Lower GLUT1 and unchanged MCT1 in Alzheimer's disease cerebrovasculature
M Leclerc, C Tremblay, P Bourassa… - Journal of Cerebral …, 2024 - journals.sagepub.com
The brain is a highly demanding organ, utilizing mainly glucose but also ketone bodies as
sources of energy. Glucose transporter-1 (GLUT1) and monocarboxylates transporter-1 …
sources of energy. Glucose transporter-1 (GLUT1) and monocarboxylates transporter-1 …
Dissociation of tau pathology and neuronal hypometabolism within the ATN framework of Alzheimer's disease
Alzheimer's disease (AD) is defined by amyloid (A) and tau (T) pathologies, with T better
correlated to neurodegeneration (N). However, T and N have complex regional relationships …
correlated to neurodegeneration (N). However, T and N have complex regional relationships …
Advit: Vision transformer on multi-modality pet images for alzheimer disease diagnosis
We present a new model trained on multi-modalities of Positron Emission Tomography
images (PET-AV45 and PET-FDG) for Alzheimer's Disease (AD) diagnosis. Unlike the …
images (PET-AV45 and PET-FDG) for Alzheimer's Disease (AD) diagnosis. Unlike the …
Thymus vulgaris Essential Oil Protects Zebrafish against Cognitive Dysfunction by Regulating Cholinergic and Antioxidants Systems
Thymus vulgaris L. is an aromatic herb used for medicinal purposes such as antimicrobial,
spasmolytic, antioxidant, anti-inflammatory, antinociceptive, antitumor, and may have …
spasmolytic, antioxidant, anti-inflammatory, antinociceptive, antitumor, and may have …
[HTML][HTML] Systematic comparison of 3D Deep learning and classical machine learning explanations for Alzheimer's Disease detection
Black-box deep learning (DL) models trained for the early detection of Alzheimer's Disease
(AD) often lack systematic model interpretation. This work computes the activated brain …
(AD) often lack systematic model interpretation. This work computes the activated brain …