Population genomics of Klebsiella pneumoniae

KL Wyres, MMC Lam, KE Holt - Nature Reviews Microbiology, 2020 - nature.com
Klebsiella pneumoniae is a common cause of antimicrobial-resistant opportunistic infections
in hospitalized patients. The species is naturally resistant to penicillins, and members of the …

Co** with the ESKAPE pathogens: Evolving strategies, challenges and future prospects

C Aloke, I Achilonu - Microbial pathogenesis, 2023 - Elsevier
Globally, the ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella
pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter …

Phage-microbe dynamics after sterile faecal filtrate transplantation in individuals with metabolic syndrome: a double-blind, randomised, placebo-controlled clinical trial …

K Wortelboer, PA de Jonge, TPM Scheithauer… - Nature …, 2023 - nature.com
Bacteriophages (phages) are bacterial viruses that have been shown to shape microbial
communities. Previous studies have shown that faecal virome transplantation can decrease …

Secondary bacterial infections in patients with viral pneumonia

P Manohar, B Loh, R Nachimuthu, X Hua… - Frontiers in …, 2020 - frontiersin.org
Pulmonary diseases of viral origin are often followed by the manifestation of secondary
infections, leading to further clinical complications and negative disease outcomes. Thus …

Intestinal phages interact with bacteria and are involved in human diseases

H Shuwen, D Kefeng - Gut Microbes, 2022 - Taylor & Francis
Phages are the most abundant and diverse biological entities on Earth and exert specific
effects on bacterial hosts. The coexistence of phages and bacteria in the intestinal tract is …

[HTML][HTML] Phage therapy for treatment of virulent Klebsiella pneumoniae infection in a mouse model

T Anand, N Virmani, S Kumar, AK Mohanty… - Journal of global …, 2020 - Elsevier
Objectives Klebsiella pneumoniae is an important emerging pathogen of humans and
animals leading to serious clinical consequences. Increased antibiotic use has promoted the …

An overview of colistin resistance, mobilized colistin resistance genes dissemination, global responses, and the alternatives to colistin: A review

MH Gharaibeh, SQ Shatnawi - Veterinary World, 2019 - pmc.ncbi.nlm.nih.gov
Colistin, also known as polymyxin E, is an antimicrobial agent that is effective against a
variety of Gram-negative bacilli, especially the Enterobacteriaceae family. Recently, the wide …

Bacteriophage Cocktails Protect Dairy Cows Against Mastitis Caused By Drug Resistant Escherichia coli Infection

M Guo, Y Gao, Y Xue, Y Liu, X Zeng… - Frontiers in cellular …, 2021 - frontiersin.org
Mastitis caused by Escherichia coli (E. coli) remains a threat to dairy animals and impacts
animal welfare and causes great economic loss. Furthermore, antibiotic resistance and the …

Secondary bacterial infections during pulmonary viral disease: phage therapeutics as alternatives to antibiotics?

P Manohar, B Loh, S Athira, R Nachimuthu… - Frontiers in …, 2020 - frontiersin.org
Secondary bacterial infections manifest during or after a viral infection (s) and can lead to
negative outcomes and sometimes fatal clinical complications. Research and development …

Analysis of selection methods to develop novel phage therapy cocktails against antimicrobial resistant clinical isolates of bacteria

MEK Haines, FE Hodges, JY Nale, J Mahony… - Frontiers in …, 2021 - frontiersin.org
Antimicrobial resistance (AMR) is a major problem globally. The main bacterial organisms
associated with urinary tract infection (UTI) associated sepsis are E. coli and Klebsiella …