Progresses in predicting post-translational modification

KC Chou - International Journal of Peptide Research and …, 2020 - Springer
Identification of the sites of post-translational modifications (PTMs) in protein, RNA, and DNA
sequences is currently a very hot topic. This is because the information thus obtained is very …

Established and in-trial GPCR families in clinical trials: a review for target selection

S Saikia, M Bordoloi, R Sarmah - Current drug targets, 2019 - ingentaconnect.com
The largest family of drug targets in clinical trials constitute of GPCRs (G-protein coupled
receptors) which accounts for about 34% of FDA (Food and Drug Administration) approved …

19F-NMR in target-based drug discovery

CB Kang - Current Medicinal Chemistry, 2019 - ingentaconnect.com
Solution NMR spectroscopy plays important roles in understanding protein structures,
dynamics and protein-protein/ligand interactions. In a target-based drug discovery project …

Recent advances in ginsenosides as potential therapeutics against breast cancer

Y Guo, R Kuruganti, Y Gao - Current Topics in Medicinal …, 2019 - ingentaconnect.com
The dried root of ginseng (Panax ginseng CA Meyer or Panax quinquefolius L.) is a
traditional Chinese medicine widely used to manage cancer symptoms and chemotherapy …

Prediction of protein N-formylation using the composition of k-spaced amino acid pairs

Z Ju, JZ Cao - Analytical Biochemistry, 2017 - Elsevier
As one of important protein post-translational modifications, N-formylation has been reported
to be involved in various biological processes. The accurate identification of N-formylation …

[HTML][HTML] Benchmark data for identifying N6-methyladenosine sites in the Saccharomyces cerevisiae genome

W Chen, P Feng, H Ding, H Lin, KC Chou - Data in brief, 2015 - Elsevier
This data article contains the benchmark dataset for training and testing iRNA-Methyl, a web-
server predictor for identifying N 6-methyladenosine sites in RNA (Chen et al., 2015 [15]). It …

Biological production of (S)-acetoin: a state-of-the-art review

NZ **e, JX Li, RB Huang - Current Topics in Medicinal …, 2019 - ingentaconnect.com
Acetoin is an important four-carbon compound that has many applications in foods, chemical
synthesis, cosmetics, cigarettes, soaps, and detergents. Its stereoisomer (S)-acetoin, a high …

DNA methylation prediction using reduced features obtained via Gappy Pair Kernel and Partial Least Square

S Shah, AU Rahman, S Jabeen, A Khan… - IEEE …, 2022 - ieeexplore.ieee.org
It is critical to correctly identify DNA methylation because it has been linked to a variety of
human disorders, particularly cancer. DNA methylation is an epigenetic process that allows …