Emerging trends in nano-driven immunotherapy for treatment of cancer

G Kandasamy, Y Karuppasamy, UM Krishnan - Vaccines, 2023 - mdpi.com
Despite advancements in the development of anticancer medications and therapies, cancer
still has the greatest fatality rate due to a dismal prognosis. Traditional cancer therapies …

Biomaterial-Based CRISPR/Cas9 Delivery Systems for Tumor Treatment

M Li, F Chen, Q Yang, Q Tang, Z **ao, X Tong… - Biomaterials …, 2024 - spj.science.org
CRISPR/Cas9 gene editing technology is characterized by high specificity and efficiency,
and has been applied to the treatment of human diseases, especially tumors involving …

Nitrogen-doped carbon dots facilitate CRISPR/Cas for reducing antibiotic resistance genes in the environment

F Chen, H Du, M Tao, L Xu, C Wang… - Journal of Agricultural …, 2024 - ACS Publications
The continued acquisition and propagation of antibiotic resistance genes (ARGs) in the
environment confound efforts to manage the global rise in antibiotic resistance. Here …

Bioorthogonal CRISPR/Cas9‐Drug Conjugate: A Combinatorial Nanomedicine Platform

MJ Beha, JC Kim, SH Im, Y Kim, S Yang… - Advanced …, 2023 - Wiley Online Library
Bioconjugation of proteins can substantially expand the opportunities in biopharmaceutical
development, however, applications are limited for the gene editing machinery despite its …

The Future of Healthcare Materials

NM Khashab, F Caruso - Chemistry of Materials, 2023 - ACS Publications
In recent years, applying nanotechnology in the medical field has been under heavy
scrutiny, largely due to challenges in the effective translation of designed materials from the …

Finely tuned ionizable lipid nanoparticles for CRISPR/Cas9 ribonucleoprotein delivery and gene editing

SH Im, M Jang, JH Park, HJ Chung - Journal of Nanobiotechnology, 2024 - Springer
Nonviral delivery of the CRISPR/Cas9 system provides great benefits for in vivo gene
therapy due to the low risk of side effects. However, in vivo gene editing by delivering the …

CRISPR/Cas9-Mediated Customizing Strategies for Adoptive T-Cell Therapy

H Park, YK Kang, G Shim - Pharmaceutics, 2024 - mdpi.com
Clustered regularly interspaced short palindromic repeat-associated protein Cas9
(CRISPR/Cas9) technology is at the forefront of cancer immunotherapy innovation, offering …

An Antibody‐CRISPR/Cas Conjugate Platform for Target‐Specific Delivery and Gene Editing in Cancer

S Yang, SH Im, JY Chung, J Lee, KH Lee… - Advanced …, 2024 - Wiley Online Library
The CRISPR/Cas system has been introduced as an innovative tool for therapy, however
achieving specific delivery to the target has been a major challenge. Here, an antibody …

Nanotechnology‐based CRISPR/Cas9 delivery system for genome editing in cancer treatment

S Zhou, Y Li, Q Wu, C Gong - MedComm–Biomaterials and …, 2024 - Wiley Online Library
The clustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR
associated protein 9 (CRISPR/Cas9) systems initiate a revolution in genome editing, which …