Thorough understanding of how to control cell behaviors including cell adhesion,
orientation, migration and differentiation on an artificial surface is critical in materials and life …

Tissue engineering holds great promise to develop functional constructs resembling the
structural organization of native tissues to improve or replace biological functions, with the …

Enabling angiogenesis is critical for the success of tissue repair therapies and the fate of
tissue-engineered constructs. Although many biochemical signaling molecules have been …

The main limitation in engineering in vitro tissues is the lack of a sufficient blood vessel
system—the vascularization. In vivo almost all tissues are supplied by these endothelial cell …

Vascularization of large bone grafts is one of the main challenges of bone tissue
engineering (BTE), and has held back the clinical translation of engineered bone constructs …

Porous biodegradable scaffolds provide a physical substrate for cells allowing them to
attach, proliferate and guide the formation of new tissues. A variety of techniques have been …

Extracellular matrix fibers (ECM) such as collagen, elastin, and keratin provide biological
and physical support for cell attachment, proliferation, migration, differentiation and …

Despite the great advances that the tissue engineering field has experienced over the last
two decades, the amount of in vitro engineered tissues that have reached a stage of clinical …

Hierarchical hybrid micro/nano-textured titanium surface topographies with titania
nanotubes were produced by simple acid etching followed by anodization to mimic the …

The selection, synthesis, modification and sha** of biomaterials are complex tasks within
the biomedical field. Human and plant tissues, such as, wood, bone and cartilage are …