Insights into lipid-protein interactions from computer simulations

DP Tieleman, BI Sejdiu, EA Cino, P Smith… - Biophysical …, 2021 - Springer
Lipid-protein interactions play an important direct role in the function of many membrane
proteins. We argue they are key players in membrane structure, modulate membrane …

The interaction of steroids with phospholipid bilayers and membranes

J Crowley, M Withana, E Deplazes - Biophysical Reviews, 2022 - Springer
Steroids are critical for various physiological processes and used to treat inflammatory
conditions. Steroids act by two distinct pathways. The genomic pathway is initiated by the …

Mechanosensitive aquaporins

M Ozu, L Galizia, JJ Alvear-Arias, M Fernández… - Biophysical …, 2023 - Springer
Cellular systems must deal with mechanical forces to satisfy their physiological functions. In
this context, proteins with mechanosensitive properties play a crucial role in sensing and …

Computational studies of Piezo1 yield insights into key lipid–protein interactions, channel activation, and agonist binding

Y Lin, A Buyan, B Corry - Biophysical Reviews, 2022 - Springer
Piezo1 is a mechanically gated ion channel responsible for converting mechanical stimuli
into electrical signals in mammals, playing critical roles in vascular development and blood …

LISTERIN E3 ubiquitin ligase and ribosome-associated quality control (RQC) mechanism

R Mishra, A Bansal, A Mishra - Molecular Neurobiology, 2021 - Springer
According to cellular demands, ribosomes synthesize and maintain the desired pool of
proteins inside the cell. However, sometimes due to defects in ribosomal machinery and …

Initiating Coarse-Grained MD Simulations for Membrane-Bound Proteins

A Buyan, B Corry - Membrane Lipids: Methods and Protocols, 2022 - Springer
Molecular dynamics (MD) simulations have become a widely used tool in the scientific
community for understanding molecular scale phenomena that are challenging to address …