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Insights into lipid-protein interactions from computer simulations
Lipid-protein interactions play an important direct role in the function of many membrane
proteins. We argue they are key players in membrane structure, modulate membrane …
proteins. We argue they are key players in membrane structure, modulate membrane …
The interaction of steroids with phospholipid bilayers and membranes
Steroids are critical for various physiological processes and used to treat inflammatory
conditions. Steroids act by two distinct pathways. The genomic pathway is initiated by the …
conditions. Steroids act by two distinct pathways. The genomic pathway is initiated by the …
Mechanosensitive aquaporins
Cellular systems must deal with mechanical forces to satisfy their physiological functions. In
this context, proteins with mechanosensitive properties play a crucial role in sensing and …
this context, proteins with mechanosensitive properties play a crucial role in sensing and …
Computational studies of Piezo1 yield insights into key lipid–protein interactions, channel activation, and agonist binding
Piezo1 is a mechanically gated ion channel responsible for converting mechanical stimuli
into electrical signals in mammals, playing critical roles in vascular development and blood …
into electrical signals in mammals, playing critical roles in vascular development and blood …
LISTERIN E3 ubiquitin ligase and ribosome-associated quality control (RQC) mechanism
According to cellular demands, ribosomes synthesize and maintain the desired pool of
proteins inside the cell. However, sometimes due to defects in ribosomal machinery and …
proteins inside the cell. However, sometimes due to defects in ribosomal machinery and …
Initiating Coarse-Grained MD Simulations for Membrane-Bound Proteins
Molecular dynamics (MD) simulations have become a widely used tool in the scientific
community for understanding molecular scale phenomena that are challenging to address …
community for understanding molecular scale phenomena that are challenging to address …