Autophagy is a catabolic pathway, which breaks down old and damaged cytoplasmic
material into basic biomolecules through lysosome-mediated digestion thereby recycling …

Our group was the first one reporting that autophagy could be triggered by airborne fine
particulate matter (PM) with a mean diameter of less than 2.5 μm (PM 2.5) in human lung …

At first, the molecular mechanism of autophagy was unveiled in a unicellular organism
Saccharomyces cerevisiae (budding yeast), followed by the discovery that the basic …

The human health hazards related to persisting use of bisphenol-A (BPA) are well
documented. BPA-induced neurotoxicity occurs with the generation of oxidative stress …

Mitophagy, a special type of autophagy, plays an important role in the mitochondria quality
control and cellular homeostasis. In this study, we examined the molecular mechanism of …

Epithelial mesenchymal transition (EMT) is a crucial morphological event during tumor
progression. The present study reported that EMT could be triggered by airborne fine …

Long-term exposure to polycyclic aromatic hydrocarbons (PAHs) and their nitrated (NPAHs)
and oxygenated (OPAHs) derivatives can cause adverse health effects due to their …

Pharmacological conditioning is a protective strategy against ischemia/reperfusion injury,
which occurs during liver resection and transplantation. Polyethylene glycols have shown …

Cigarette smoking causes emphysema, a fatal disease involving extensive structural and
functional damage of the lung. Using a guinea pig model and human lung cells, we show …

During the last decades, the potential harmfulness derived from the exposure to
environmental pollutants has been largely demonstrated, with associated damages ranging …