Structurally diversified heterocycles and related privileged scaffolds as potential urease inhibitors: a brief overview

A Ibrar, I Khan, N Abbas - Archiv der Pharmazie, 2013 - Wiley Online Library
Ureases have emerged as significant virulence factors implicated in the pathogenesis of
many clinical conditions such as pyelonephritis, hepatic coma, peptic ulceration, and the …

Metal complexes as urease inhibitors

L Habala, F Devínsky, AE Egger - Journal of coordination chemistry, 2018 - Taylor & Francis
Urease plays a significant role in the pathogenesis of several diseases and also has
practical implications in other fields, such as agriculture or chemical analysis. Among the …

Coordination Behavior of N,N′,N″-Trisubstituted Guanidine Ligands in Their Ru–Arene Complexes: Synthetic, DNA/Protein Binding, and Cytotoxic Studies

K Jeyalakshmi, J Haribabu, C Balachandran… - …, 2019 - ACS Publications
Ruthenium complexes are fascinating for exploration as anticancer drugs after the entry of
KP1019 and NAMI-A in phase II clinical trials for the treatment of metastatic tumors. The …

DNA/protein binding, DNA cleavage, cytotoxicity, superoxide radical scavenging and molecular docking studies of copper (II) complexes containing N-benzyl-N′-aryl …

K Jeyalakshmi, Y Arun, NSP Bhuvanesh… - Inorganic Chemistry …, 2015 - pubs.rsc.org
Five copper (II) complexes containing N, N′, N′′-trisubstituted guanidine ligands were
synthesized and characterized by elemental analyses and UV-Visible, FT-IR, EPR and mass …

Synthesis, crystal structures, and urease inhibition of an acetohydroxamate-coordinated oxovanadium (V) complex derived from N′-(3-bromo-2-hydroxybenzylidene) …

D Qu, F Niu, X Zhao, KX Yan, YT Ye, J Wang… - Bioorganic & medicinal …, 2015 - Elsevier
A new benzohydrazone compound N′-(3-bromo-2-hydroxybenzylidene)-4-
methoxybenzohydrazide (H 2 L) was prepared. Reaction of H 2 L and acetohydroxamic acid …

Ferrocene-based guanidine derivatives: In vitro antimicrobial, DNA binding and docking supported urease inhibition studies

R Gul, MK Rauf, A Badshah, SS Azam, MN Tahir… - European journal of …, 2014 - Elsevier
Some novel ferrocenyl guanidines 1–8 were synthesized and characterized by different
spectroscopic methods, elemental analysis and single crystal X-rays diffraction techniques …

Ferrocene-functionalized anilines as potent anticancer and antidiabetic agents: Synthesis, spectroscopic elucidation, and DFT calculations

F Asghar, S Munir, S Fatima, B Murtaza, J Patujo… - Journal of Molecular …, 2022 - Elsevier
Ferrocene derivatives have attracted significant interest as potent biological agents and
novel drug candidates. Hence, the present research work was focused on the synthesis and …

Preparation and Characterization of Zwitterionic Poly(β‐cyclodextrin‐co‐guanidinocitrate) Hydrogels for Ciprofloxacin Controlled Release

A Heydari, A Pardakhti… - … Materials and Engineering, 2017 - Wiley Online Library
A facile, safe, and environmentally friendly approach to the preparation of poly (β‐
cyclodextrin‐co‐guanidinocitrate)(ZWβCDP) via polymerization of β‐cyclodextrin (β‐CD) in …

DNA/protein binding and cytotoxicity studies of copper (ii) complexes containing N, N′, N′′-trisubstituted guanidine ligands

K Jeyalakshmi, N Selvakumaran, NSP Bhuvanesh… - RSC Advances, 2014 - pubs.rsc.org
A series of N, N′, N′′-trisubstituted guanidine ligands (L1–L5) and their copper (II)
complexes (1–5)[Cu (II){C4H3SCONC (NHR) NC6H5} 2][where R= p-tolyl (1), phenyl (2) …

Synthesis, crystal structures of oxovanadium (V) complexes with hydrazone ligands and their catalytic performance for the styrene oxidation

Y Zhang, T Yang, BY Zheng, MY Liu, N **ng - Polyhedron, 2017 - Elsevier
Four new oxovanadium (V) complexes,[VO (aha) L 1](1),[VO (aha) L 2](2),[VO (aha) L 3](3),
and [VO (aha) L 4]· EtOH (4)(Haha= acetohydroxamic acid, H 2 L 1= 4-nitrophenyl 2-(2 …