HDL and cardiovascular disease: atherogenic and atheroprotective mechanisms

M Navab, ST Reddy, BJ Van Lenten… - Nature Reviews …, 2011 - nature.com
The lipoprotein HDL has two important roles: first, it promotes reverse cholesterol transport,
and second, it modulates inflammation. Epidemiological studies show that HDL-cholesterol …

[HTML][HTML] The epidemiology of atherosclerotic cardiovascular disease among patients with SLE: a systematic review

SR Schoenfeld, S Kasturi, KH Costenbader - Seminars in arthritis and …, 2013 - Elsevier
Objective To perform a systematic review of the literature regarding the epidemiology of the
association between systemic lupus erythematosus (SLE) and atherosclerotic …

Atualização da diretriz brasileira de dislipidemias e prevenção da aterosclerose–2017

AA Faludi, MCO Izar, JFK Saraiva… - Arquivos brasileiros de …, 2017 - SciELO Brasil
Material de distribuição exclusiva à classe médica. Os Arquivos Brasileiros de Cardiologia
não se responsabilizam pelo acesso indevido a seu conteúdo e que contrarie a …

Phase 1 double-blind randomized safety trial of the Janus kinase inhibitor tofacitinib in systemic lupus erythematosus

SA Hasni, S Gupta, M Davis, E Poncio… - Nature …, 2021 - nature.com
Increased risk of premature cardiovascular disease (CVD) is well recognized in systemic
lupus erythematosus (SLE). Aberrant type I-Interferon (IFN)-neutrophil interactions contribute …

Taming lupus—a new understanding of pathogenesis is leading to clinical advances

Z Liu, A Davidson - Nature medicine, 2012 - nature.com
Systemic lupus erythematosus (SLE) is an autoimmune disease that is characterized by the
loss of tolerance to nuclear self antigens, the production of pathogenic autoantibodies and …

Glucagonlike peptide 1–based therapies and risk of hospitalization for acute pancreatitis in type 2 diabetes mellitus: a population-based matched case-control study

S Singh, HY Chang, TM Richards… - JAMA internal …, 2013 - jamanetwork.com
Importance Acute pancreatitis has significant morbidity and mortality. Previous studies have
raised the possibility that glucagonlike peptide 1 (GLP-1)–based therapies, including a GLP …

Lipid metabolism in autoimmune rheumatic disease: implications for modern and conventional therapies

G Robinson, I Pineda-Torra, C Ciurtin… - The Journal of …, 2022 - Am Soc Clin Investig
Suppressing inflammation has been the primary focus of therapies in autoimmune rheumatic
diseases (AIRDs), including rheumatoid arthritis and systemic lupus erythematosus …

Cardiovascular disease in systemic lupus erythematosus: a comprehensive update

M Giannelou, CP Mavragani - Journal of autoimmunity, 2017 - Elsevier
Heightened rates of both cardiovascular (CV) events and subclinical atherosclerosis,
documented by imaging and vascular function techniques are well established in systemic …

Neutrophil extracellular trap–derived enzymes oxidize high‐density lipoprotein: an additional proatherogenic mechanism in systemic lupus erythematosus

CK Smith, A Vivekanandan‐Giri, C Tang… - Arthritis & …, 2014 - Wiley Online Library
Objective Oxidative stress and oxidized high‐density lipoprotein (HDL) are implicated as risk
factors for cardiovascular disease (CVD) in systemic lupus erythematosus (SLE). Yet, how …

Accelerated atherosclerosis in patients with SLE—mechanisms and management

BJ Skaggs, BH Hahn, M McMahon - Nature Reviews Rheumatology, 2012 - nature.com
Rapid-onset cardiovascular disease (CVD) is a major concern for many patients with
systemic lupus erythematosus (SLE). Cardiovascular events occur more frequently and with …