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Hypericin and its anticancer effects: From mechanism of action to potential therapeutic application
Background Emerging studies indicate that hypericin has diverse pharmacological actions
and exhibits potential for treatment of various types of cancer. Purpose The current review …
and exhibits potential for treatment of various types of cancer. Purpose The current review …
Hypericin as a promising natural bioactive naphthodianthrone: A review of its pharmacology, pharmacokinetics, toxicity, and safety
Z Peng, J Lu, K Liu, L **e, Y Wang, C Cai… - Phytotherapy …, 2023 - Wiley Online Library
Hypericin can be derived from St. John's wort, which is widely spread around the world. As a
natural product, it has been put into clinical practice such as wound healing and depression …
natural product, it has been put into clinical practice such as wound healing and depression …
Structural Characterization and Anticancer Activity of a New Anthraquinone from Senna velutina (Fabaceae)
DTH Castro, DF Leite, D da Silva Baldivia… - Pharmaceuticals, 2023 - mdpi.com
In this study, a novel compound was isolated, identified, and its chemical structure was
determined from the extract of the roots of Senna velutina. In addition, we sought to evaluate …
determined from the extract of the roots of Senna velutina. In addition, we sought to evaluate …
Anti-cancer impact of Hypericin in B-CPAP cells: Extrinsic caspase dependent apoptosis induction and metastasis obstruction
M Piryaei, B Mehrparvar, A Mohammadian… - European Journal of …, 2021 - Elsevier
Thyroid cancer is the most common type of endocrine-related cancer. According to the
literature, its incidence is not very high, but its rate increasing especially in developed …
literature, its incidence is not very high, but its rate increasing especially in developed …
Transcriptome analysis evinces anti-neoplastic mechanisms of hypericin: A study on U87 glioblastoma cell line
Abstract Aims Hypericin (HYP) from Hypericum perforatum has cytotoxic effects on a variety
of malignant cell types, but the pattern of gene expression mediating the effect is largely …
of malignant cell types, but the pattern of gene expression mediating the effect is largely …
Fluorescence-Guided Laparoscopy after Oral Hypericin Administration for Staging of Locally Advanced Gastric Cancer—A Pilot Study
C Yurttas, P Horvath, I Fischer, S Wagner… - Journal of Clinical …, 2024 - mdpi.com
(1) Background: Laparoscopic staging is essential in gastric cancer (GC) to rule out
peritoneal metastasis (PM). Hypericin, a plant-derived fluorescent compound, has been …
peritoneal metastasis (PM). Hypericin, a plant-derived fluorescent compound, has been …
Hypericin-mediated regulation of miR21 and miR34a and their target genes in MCF7 breast cancer cells
R Norouzi, S Ghotbzadeh-Kermani… - Revista Brasileira de …, 2023 - Springer
Hypericin is a polyphenolic compound derived from Hypericum perforatum L.,
Hypericaceae, that exhibits cytotoxic activity in various cancer cell types. The molecular …
Hypericaceae, that exhibits cytotoxic activity in various cancer cell types. The molecular …
Inhibition by Hypericin of Tongue Squamous Carcinoma Cell Proliferation and Treatment of Resistance in Dental Pulp Stem Cells
Tongue cancer is a malignancy affecting the head and neck region that has exhibited an
increased incidence in recent decades, primarily attributed to alterations in lifestyle patterns …
increased incidence in recent decades, primarily attributed to alterations in lifestyle patterns …
[PDF][PDF] Antitumor activity and phenolic profile of Melissa officinalis extract against human gastric adenocarcinoma cells.
Gastric cancer remains a global health concern, driving the exploration of natural products
with anticancer potential. This study investigated the antiproliferative activity and chemical …
with anticancer potential. This study investigated the antiproliferative activity and chemical …
Study on antioxidant and cytotoxic properties of Ephedra major Host. hydroalcoholic extract on AGS gastric carcinoma cell line.
F Moraghebi, SA Yamchelo, SM Maddah - 2023 - cabidigitallibrary.org
Gastric cancer is a malignant tumor that is one of the most common types of cancer in the
world and Iran. Plants are rich sources of a variety of antioxidant compounds which can be …
world and Iran. Plants are rich sources of a variety of antioxidant compounds which can be …