A comprehensive knowledge of the types and ratios of microbes that inhabit the healthy
human gut is necessary before any kind of pre-clinical or clinical study can be performed …

The human gastrointestinal (gut) microbiome plays a critical role in maintaining host health
and has been increasingly recognized as an important factor in precision medicine. High …

With the rapid development of human intestinal microbiology and diverse microbiome-
related studies and investigations, a large amount of data have been generated and …

Background Recently, studies have suggested a role for the gut microbiota in epilepsy. Gut
microbial changes during ketogenic diet (KD) treatment of drug-resistant epilepsy have been …

Motivation Biological rhythms, such as rhythms in gene expression controlled by the cell
cycle or the circadian clock, are important in cell physiology. A common type of experiment …

Background & Aims We studied interactions among proteins of the carcinoembryonic
antigen-related cell adhesion molecule (CEACAM) family, which interact with microbes, and …

Abstract The High-performance Integrated Virtual Environment (HIVE) is a distributed
storage and compute environment designed primarily to handle next-generation sequencing …

Motivation: High-throughput metagenomic sequencing has revolutionized our view on the
structure and metabolic potential of microbial communities. However, analysis of …

High-throughput sequencing (HTS) has demonstrated capabilities for broad virus detection
based upon discovery of known and novel viruses in a variety of samples, including clinical …

Background Unbiased deep sequencing offers the potential for improved adventitious virus
screening in vaccines and biotherapeutics. Successful implementation of such assays will …