There is now strong evidence of progressive neuropathological processes in bipolar
disorder (BD). On this basis, the current understanding of the neurobiology of BD has shifted …

▪ Abstract This chapter reviews recent research on the relationship between stressful life
experiences and depression. A distinction is made between aggregate studies of overall …

Bipolar disorder is heterogeneous in phenomenology, illness trajectory, and response to
treatment. Despite evidence for the efficacy of multimodality interventions, the majority of …

This the Diagnostic Interview for Genetic Studies (DIGS), a clinical interview especially
constructed for the assessment of major mood and psychotic disorders and their spectrum …

Objectives. These guidelines are based on a first edition that was published in 2004, and
have been edited and updated with the available scientific evidence up to October 2012 …

OBJECTIVE: The recurrence of an affective disorder in people who initially recover from
major depressive disorder was characterized by using the unique longitudinal prospective …

Abstract Members of the National Depressive and Manic-Depressive Association who have
bipolar disorder were surveyed. 59% of respondents had their first symptoms during …

Sex is clearly important in unipolar mood disorder with compelling evidence that depression
is approximately twice as common in women than in men. In the case of bipolar disorder …

A review of two centuries' literature on the natural history of bipolar disorder, including
modern naturalistic studies and new data from a lifelong follow-up study of 220 bipolar …

Objective: To present nationally representative data on 12-month and lifetime prevalence,
correlates, and comorbidity of bipolar I disorder. Method: The data were derived from the …