Leishmania are obligate intracellular parasites of mononuclear phagocytes transmitted by
Phlebotomine sandflies. Monocytes are one of the main cell types recruited to the site of the …

Neutrophils with their array of microbicidal activities are the first innate immune cells to
guard against infection. They are also most crucial for the host's initial defense against …

Leishmaniasis is a neglected tropical infectious disease with thousands of cases annually; it
is of great concern to global health, particularly the most severe form, visceral leishmaniasis …

Visceral leishmaniasis (VL) is the most lethal among all leishmaniasis diseases and remains
categorized as a neglected tropical disease (NTD). This study aimed to develop a peptide …

Human cutaneous leishmaniasis (CL) caused by Leishmania braziliensis is characterized
by a pronounced inflammatory response associated with ulcer development. Monocytes …

Visceral leishmaniasis (VL) is a chronic and fatal disease caused by Leishmania infantum in
Brazil. Leukocyte recruitment to infected tissue is a crucial event for the control of infections …

Visceral leishmaniasis (VL) is an infectious disease caused by Leishmania infantum (L.
infantum). Currently, there are no vaccines and/or prophylactic therapies against VL, and the …

Abstract Toll‐like receptors (TLRs), members of pattern recognition receptors, are expressed
on many cells of the innate immune system, and their engagements with antigens regulate …

Background A wide spectrum of clinical manifestations and immune responses exist in
canine L. infantum infection. Ibizan hounds are more “resistant” to disease than other dog …

Human infection with different species of Leishmania leads to distinct clinical manifestations,
ranging from relatively mild cutaneous (Leishmania braziliensis) to severe visceral …