Traumatic, tumoral, and infectious bone defects are common in clinics, and create a big
burden on patient's families and society. Calcium phosphate (CaP)-based biomaterials have …

Tissue and organ development during embryogenesis relies on the collective and
coordinated action of many cells. Recent studies have revealed that tissue material …

Cell adhesion molecules are ubiquitous in multicellular organisms, specifying precise cell–
cell interactions in processes as diverse as tissue development, immune cell trafficking and …

Surface curvature both emerges from, and influences the behavior of, living objects at length
scales ranging from cell membranes to single cells to tissues and organs. The relevance of …

The cytoskeleton of animal cells is one of the most complicated and functionally versatile
structures, involved in processes such as endocytosis, cell division, intra-cellular transport …

Tumor vasculature creates a hostile tumor microenvironment (TME) in vivo and nourishes
cancers, resulting in cancer progression and drug resistance. To mimic the biochemical and …

The maintenance of tissue homeostasis is critically dependent on the function of tissue-
resident immune cells and the differentiation capacity of tissue-resident stem cells (SCs) …

Recent evidence clearly shows that cells respond to various physical cues in their
environments, guiding many cellular processes and tissue morphogenesis, pathology, and …

Cell–cell apical junctions of epithelia consist of multiprotein complexes that organize as
belts regulating cell–cell adhesion, permeability, and mechanical tension: the tight junction …

The ability of cells to respond to mechanical forces is critical for numerous biological
processes. Emerging evidence indicates that external mechanical forces trigger changes in …