Neutrophil gelatinase-associated lipocalin (NGAL) is a 25-kDa protein that is secreted
mostly by immune cells such as neutrophils, macrophages, and dendritic cells. Its production …

Abstract Lipocalin-2 (LCN-2) is a novel, 198 amino acid adipocytokine also referred to as
neutrophil gelatinase-associated lipocalin (NGAL). LCN-2 is a circulatory protein …

Distant metastasis is a primary cause of mortality and contributes to poor surgical outcomes
in cancer patients. Before the development of organ-specific metastasis, the formation of a …

Alcoholic liver disease (ALD) is a complex process that includes a wide spectrum of hepatic
lesions, from steatosis to cirrhosis. Cell injury, inflammation, oxidative stress, regeneration …

Hepatocytes, the major parenchymal cells in the liver, play pivotal roles in metabolism,
detoxification, and protein synthesis. Hepatocytes also activate innate immunity against …

Lipocalin-2 (LCN2), also known as neutrophil gelatinase-associated lipocalin (NGAL), is
released by various cell types and is an attractive biomarker of inflammation, ischemia …

Chronic stress induces anxiety disorders via both neural pathways and circulating factors.
Although many studies have elucidated the neural circuits involved in stress-co** …

Abstract Lipocalin 2 (LCN2) was recently identified as an endogenous ligand of the type 4
melanocortin receptor (MC4R), a critical regulator of appetite. However, it remains unknown …

Chronic liver injury with any etiology can progress to fibrosis and the end-stage diseases
cirrhosis and hepatocellular carcinoma. The progression of liver disease is controlled by a …

Chronic (neuro) inflammation plays an important role in many age-related central nervous
system (CNS) diseases, including Alzheimer's disease, Parkinson's disease and vascular …