Bacteria often encounter temperature fluctuations in their natural habitats and must adapt to
survive. The molecular response of bacteria to sudden temperature upshift or downshift is …

RNA-binding proteins (RBPs) are central to most if not all cellular processes, dictating the
fate of virtually all RNA molecules in the cell. Starting with pioneering work on ribosomal …

CspA, the major cold-shock protein of Escherichia coli, is dramatically induced during the
cold-shock response. The amino acid sequence of CspA shows 43% identity to the" cold …

Presented is a polarizable force field based on a classical Drude oscillator framework,
currently implemented in the programs CHARMM and NAMD, for modeling and molecular …

This review describes the structure and functions of Y-box binding protein 1 (YB-1) and its
homologs. Interactions of YB-1 with DNA, mRNAs, and proteins are considered. Data on the …

“Bacteria have evolved adaptive networks to face the challenges of changing environments
and to survive under conditions of stress. Therefore, the efficiencies of inactivation and …

▪ Abstract Beginning with simplified lattice and continuum “minimalist” models and
progressing to detailed atomic models, simulation studies have augmented and directed …

Members of a family of cold-shock proteins (CSPs) are found throughout the eubacterial
domain and appear to function as RNA-chaperones. They have been implicated in various …

The millisecond time scale needed for molecular dynamics simulations to approach the
quantitative study of protein folding is not yet routine. One approach to extend the simulation …

The heterochronic gene lin-28 is a regulator of developmental timing in the nematode
Caenorhabditis elegans. It must be expressed in the first larval stage and downregulated by …