This report provides a review of early and late effects of radiation in normal tissues and
organs with respect to radiation protection. It was instigated following a recommendation in …

Purpose: Total body irradiation (TBI) and chemotherapy are common components of
conditioning regimens for bone marrow transplantation. Interstitial pneumonitis (IP) is a …

The relative biological effectiveness (RBE) of protons varies with multiple physical and
biological factors. Phenomenological RBE models have been developed to include such …

Purpose: To describe the radiobiological rationale for dose-per-fraction escalation in non–
small-cell lung cancer (NSCLC) and to devise a novel Phase I scheme to implement this …

Purpose Radiation pneumonitis (RP) is commonly associated with thoracic radiation
therapy, and its incidence is related to dose and volume of the normal lung in the path of …

PURPOSE: To show that radiotherapy (RT) dose to the noninvolved extended field (EF) can
be reduced without loss of efficacy in patients with early-stage Hodgkin's disease (HD) …

Intraoperative radiotherapy differs from conventional, fractionated radiotherapy in several
aspects that may influence its biological effect. The radiation quality influences the relative …

Background and purpose: Radiotherapy is a treatment method frequently employed in the
management of thoracic tumours. Although the highest incidence of these tumours is found …

To be able to predict the impact of any radiotherapy treatment the physics of radiation
interactions and the expected biological effect for any radiotherapy treatment situation (dose …

Purpose: To quantify the influence of treatment-and patient-related factors on the severity of
early local pulmonary injury and to establish whether regional differences are present for …