Fusion protein linkers: property, design and functionality
As an indispensable component of recombinant fusion proteins, linkers have shown
increasing importance in the construction of stable, bioactive fusion proteins. This review …
increasing importance in the construction of stable, bioactive fusion proteins. This review …
Research progress of multi-enzyme complexes based on the design of scaffold protein
X Wang, Y Jiang, H Liu, H Yuan, D Huang… - Bioresources and …, 2023 - Springer
Multi-enzyme complexes designed based on scaffold proteins are a current topic in
molecular enzyme engineering. They have been gradually applied to increase the …
molecular enzyme engineering. They have been gradually applied to increase the …
A computational approach to optimising laccase-mediated polyethylene oxidation through carbohydrate-binding module fusion
M Gollan, G Black, J Munoz-Munoz - BMC biotechnology, 2023 - Springer
Plastic pollution is a major global concern to the health and wellbeing of all terrestrial and
marine life. However, no sustainable method for waste management is currently viable. This …
marine life. However, no sustainable method for waste management is currently viable. This …
Peptide linker increased the stability of pneumococcal fusion protein vaccine candidate
L Zane, S Kraschowetz, MM Trentini… - … in Bioengineering and …, 2023 - frontiersin.org
Streptococcus pneumoniae is a bacterial pathogen exclusive to humans, responsible for
respiratory and systemic diseases. Pneumococcal protein vaccines have been proposed as …
respiratory and systemic diseases. Pneumococcal protein vaccines have been proposed as …
Structural basis of development of multi-epitope vaccine against Middle East respiratory syndrome using in silico approach
Background: Middle East respiratory syndrome (MERS) is caused by MERS coronavirus
(MERS-CoV). Thus far, MERS outbreaks have been reported from Saudi Arabia (2013 and …
(MERS-CoV). Thus far, MERS outbreaks have been reported from Saudi Arabia (2013 and …
Design of novel multi-epitope vaccines against severe acute respiratory syndrome validated through multistage molecular interaction and dynamics
Severe acute respiratory syndrome (SARS) is endemic in South China and is continuing to
spread worldwide since the 2003 outbreak, affecting human population of 37 countries till …
spread worldwide since the 2003 outbreak, affecting human population of 37 countries till …
Immunotoxins immunotherapy against hepatocellular carcinoma: a promising prospect
Hepatocellular carcinoma (HCC) is one of the most common cancers in the world. Therefore,
fighting against such cancer is reasonable. Chemotherapy drugs are sometimes inefficient …
fighting against such cancer is reasonable. Chemotherapy drugs are sometimes inefficient …
Bioinformatics predictions, expression, purification and structural analysis of the PE38KDEL-scfv immunotoxin against EPHA2 receptor
E Rezaie, A Bidmeshki Pour, J Amani… - International Journal of …, 2020 - Springer
Various strategies have been proposed for treatment of cancer, including common therapies
such as surgery, chemotherapy, radiation therapy and advanced therapies such as …
such as surgery, chemotherapy, radiation therapy and advanced therapies such as …
3CL hydrolase‐based multiepitope peptide vaccine against SARS‐CoV‐2 using immunoinformatics
The present study provides the first multiepitope vaccine construct using the 3CL hydrolase
protein of SARS‐CoV‐2. The coronavirus 3CL hydrolase (Mpro) enzyme is essential for …
protein of SARS‐CoV‐2. The coronavirus 3CL hydrolase (Mpro) enzyme is essential for …
Potent in vitro antitumor activity of B-subunit of Shiga toxin conjugated to the diphtheria toxin against breast cancer
Immunotoxins are protein-based drugs consist of a target-specific binding domain and a
cytotoxic domain to eliminate target cells. Such compounds are potentially therapeutic to …
cytotoxic domain to eliminate target cells. Such compounds are potentially therapeutic to …