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Neuroinflammatory mechanisms of blood-brain barrier damage in ischemic stroke
As part of the neurovascular unit, the blood-brain barrier (BBB) is a unique, dynamic
regulatory boundary that limits and regulates the exchange of molecules, ions, and cells …
regulatory boundary that limits and regulates the exchange of molecules, ions, and cells …
Heart disease and stroke statistics—2017 update: a report from the American Heart Association
Summary Each year, the American Heart Association (AHA), in conjunction with the Centers
for Disease Control and Prevention, the National Institutes of Health, and other government …
for Disease Control and Prevention, the National Institutes of Health, and other government …
A thrombin‐activated peptide‐templated nanozyme for remedying ischemic stroke via thrombolytic and neuroprotective actions
Ischemic stroke (IS) is one of the most common causes of disability and death. Thrombolysis
and neuroprotection are two current major therapeutic strategies to overcome ischemic and …
and neuroprotection are two current major therapeutic strategies to overcome ischemic and …
Cell death pathways in ischemic stroke and targeted pharmacotherapy
Ischemic stroke is one of the significant causes of morbidity and mortality, affecting millions
of people across the globe. Cell injury in the infarct region is an inevitable consequence of …
of people across the globe. Cell injury in the infarct region is an inevitable consequence of …
Heart disease and stroke statistics—2016 update: a report from the American Heart Association
D Mozaffarian, EJ Benjamin, AS Go, DK Arnett… - circulation, 2016 - ahajournals.org
Summary Each year, the American Heart Association (AHA), in conjunction with the Centers
for Disease Control and Prevention, the National Institutes of Health, and other government …
for Disease Control and Prevention, the National Institutes of Health, and other government …
Simultaneous blood–brain barrier crossing and protection for stroke treatment based on edaravone-loaded ceria nanoparticles
Q Bao, P Hu, Y Xu, T Cheng, C Wei, L Pan, J Shi - ACS nano, 2018 - ACS Publications
Cerebral vasculature and neuronal networks will be largely destroyed due to the oxidative
damage by overproduced reactive oxygen species (ROS) during a stroke, accompanied by …
damage by overproduced reactive oxygen species (ROS) during a stroke, accompanied by …
Animal models of ischemic stroke and their application in clinical research
F Fluri, MK Schuhmann… - Drug design, development …, 2015 - Taylor & Francis
This review outlines the most frequently used rodent stroke models and discusses their
strengths and shortcomings. Mimicking all aspects of human stroke in one animal model is …
strengths and shortcomings. Mimicking all aspects of human stroke in one animal model is …
Acute stroke intervention: a systematic review
Importance Acute ischemic stroke is a major cause of mortality and morbidity in the United
States. We review the latest data and evidence supporting catheter-directed treatment for …
States. We review the latest data and evidence supporting catheter-directed treatment for …
Guidelines for the early management of patients with acute ischemic stroke: a guideline for healthcare professionals from the American Heart Association/American …
Background and Purpose—The authors present an overview of the current evidence and
management recommendations for evaluation and treatment of adults with acute ischemic …
management recommendations for evaluation and treatment of adults with acute ischemic …
Time to treatment with intravenous tissue plasminogen activator and outcome from acute ischemic stroke
Importance Randomized clinical trials suggest the benefit of intravenous tissue-type
plasminogen activator (tPA) in acute ischemic stroke is time dependent. However, modest …
plasminogen activator (tPA) in acute ischemic stroke is time dependent. However, modest …