Ultrasmall noble metal nanoparticles: Breakthroughs and biomedical implications

X Jiang, B Du, Y Huang, J Zheng - Nano today, 2018 - Elsevier
As a bridge between individual atoms and large plasmonic nanoparticles, ultrasmall (core
size< 3 nm) noble metal nanoparticles (UNMNPs) have been serving as model for us to …

Renal clearable luminescent gold nanoparticles: from the bench to the clinic

M Yu, J Xu, J Zheng - Angewandte Chemie International …, 2019 - Wiley Online Library
With more and more engineered nanoparticles (NPs) being translated to the clinic, the
United States Food and Drug Administration (FDA) has recently issued the latest draft …

A 2D nanoradiosensitizer enhances radiotherapy and delivers STING agonists to potentiate cancer immunotherapy

T Luo, GT Nash, X Jiang, X Feng, J Mao… - Advanced …, 2022 - Wiley Online Library
Despite potent preclinical antitumor activity, activation of stimulator of interferon genes
(STING) has shown modest therapeutic effects in clinical studies. Many STING agonists …

Monte Carlo Simulation‐Guided Design of a Thorium‐Based Metal–Organic Framework for Efficient Radiotherapy‐Radiodynamic Therapy

Z Xu, T Luo, J Mao, C McCleary… - Angewandte Chemie …, 2022 - Wiley Online Library
High‐Z metal‐based nanoscale metal–organic frameworks (nMOFs) with photosensitizing
ligands can enhance radiation damage to tumors via a unique radiotherapy‐radiodynamic …

The rational design and biological mechanisms of nanoradiosensitizers

H Sun, X Wang, S Zhai - Nanomaterials, 2020 - mdpi.com
Radiotherapy (RT) has been widely used for cancer treatment. However, the intrinsic
drawbacks of RT, such as radiotoxicity in normal tissues and tumor radioresistance …

The effect of nanoparticle coating on biological, chemical and biophysical parameters influencing radiosensitization in nanoparticle-aided radiation therapy

E Mansouri, A Mesbahi, H Hamishehkar… - BMC chemistry, 2023 - Springer
Nanoparticle-based composites have the potential to meet requirements for
radiosensitization in both therapeutic and diagnostic applications. The radiosensitizing …

Ultrasmall Gold Nanoparticles Radiolabeled with Iodine-125 as Potential New Radiopharmaceutical

R Wang, H Liu, B Antal, HT Wolterbeek… - ACS Applied Bio …, 2024 - ACS Publications
The relatively high linear energy transfer of Auger electrons, which can cause clustered DNA
damage and hence efficient cell death, makes Auger emitters excellent candidates for …

Glutathione-Coated Au29(SG)27: Structural Determination Based on Different Combination Styles Confirmed by Experiments

K Wang, W Su, F Gao, X Gao, W Niu… - The Journal of …, 2019 - ACS Publications
Glutathione-coated small-sized gold nanocluster denoted as Au29 (SG) 27 has potential
applications in bio therapeutics. Because it is difficult to obtain an accurate atomic structure …

Medical Applications of X-Ray Nanochemistry

T Guo, T Guo - X-ray Nanochemistry: Concepts and Development, 2018 - Springer
Three main aspects of medical applications of X-ray nanochemistry are discussed in this
chapter. The first part is enhanced X-ray imaging of tumors in animals or phantoms using X …