Enrichment effects on adult cognitive development: can the functional capacity of older adults be preserved and enhanced?
In this monograph, we ask whether various kinds of intellectual, physical, and social
activities produce cognitive enrichment effects—that is, whether they improve cognitive …
activities produce cognitive enrichment effects—that is, whether they improve cognitive …
Neurogenesis and exercise: past and future directions
H Van Praag - Neuromolecular medicine, 2008 - Springer
Research in humans and animals has shown that exercise improves mood and cognition.
Physical activity also causes a robust increase in neurogenesis in the dentate gyrus of the …
Physical activity also causes a robust increase in neurogenesis in the dentate gyrus of the …
High impact running improves learning
Regular physical exercise improves cognitive functions and lowers the risk for age-related
cognitive decline. Since little is known about the nature and the timing of the underlying …
cognitive decline. Since little is known about the nature and the timing of the underlying …
Aerobic exercise improves hippocampal function and increases BDNF in the serum of young adult males
ÉW Griffin, S Mullally, C Foley, SA Warmington… - Physiology & …, 2011 - Elsevier
Physical activity has been reported to improve cognitive function in humans and rodents,
possibly via a brain-derived neurotrophic factor (BDNF)-regulated mechanism. In this study …
possibly via a brain-derived neurotrophic factor (BDNF)-regulated mechanism. In this study …
Calcium and neurodegeneration
MP Mattson - Aging cell, 2007 - Wiley Online Library
When properly controlled, Ca2+ fluxes across the plasma membrane and between
intracellular compartments play critical roles in fundamental functions of neurons, including …
intracellular compartments play critical roles in fundamental functions of neurons, including …
Glutamate and neurotrophic factors in neuronal plasticity and disease
MP Mattson - Annals of the New York Academy of Sciences, 2008 - Wiley Online Library
Glutamate's role as a neurotransmitter at synapses has been known for 40 years, but
glutamate has since been shown to regulate neurogenesis, neurite outgrowth …
glutamate has since been shown to regulate neurogenesis, neurite outgrowth …
Exercise counteracts declining hippocampal function in aging and Alzheimer's disease
Alzheimer's disease (AD) afflicts more than 5.4 million Americans and ranks as the most
common type of dementia (Thies and Bleiler, 2011), yet effective pharmacological …
common type of dementia (Thies and Bleiler, 2011), yet effective pharmacological …
Exercise training improves memory performance in older adults: a narrative review of evidence and possible mechanisms
As human life expectancy increases, cognitive decline and memory impairment threaten
independence and quality of life. Therefore, finding prevention and treatment strategies for …
independence and quality of life. Therefore, finding prevention and treatment strategies for …
The effects of forced exercise on hippocampal plasticity in the rat: A comparison of LTP, spatial-and non-spatial learning
RM O'Callaghan, R Ohle, ÁM Kelly - Behavioural brain research, 2007 - Elsevier
Physical activity may have the potential to improve cognitive function. Here we show that
forced treadmill-running results in selective improvements in hippocampal plasticity. Rats …
forced treadmill-running results in selective improvements in hippocampal plasticity. Rats …
Running exercise protects the substantia nigra dopaminergic neurons against inflammation-induced degeneration via the activation of BDNF signaling pathway
Parkinson's disease (PD) is characterized by a progressive and selective loss of
dopaminergic (DA) neurons in the substantia nigra (SN). Although the etiology of PD …
dopaminergic (DA) neurons in the substantia nigra (SN). Although the etiology of PD …