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Immune responses to stroke: mechanisms, modulation, and therapeutic potential
Stroke is the second leading cause of death worldwide and a leading cause of disability.
Most strokes are caused by occlusion of a major cerebral artery, and substantial advances …
Most strokes are caused by occlusion of a major cerebral artery, and substantial advances …
Immune pathways in etiology, acute phase, and chronic sequelae of ischemic stroke
Inflammation and immune mechanisms are crucially involved in the pathophysiology of the
development, acute damage cascades, and chronic course after ischemic stroke …
development, acute damage cascades, and chronic course after ischemic stroke …
Discovery and validation of biomarkers to aid the development of safe and effective pain therapeutics: challenges and opportunities
Pain medication plays an important role in the treatment of acute and chronic pain
conditions, but some drugs, opioids in particular, have been overprescribed or prescribed …
conditions, but some drugs, opioids in particular, have been overprescribed or prescribed …
Post-stroke cognitive impairment: epidemiology, risk factors, and management
YY Huang, SD Chen, XY Leng, K Kuo… - Journal of …, 2022 - content.iospress.com
Stroke, characterized as a neurological deficit of cerebrovascular cause, is very common in
older adults. Increasing evidence suggests stroke contributes to the risk and severity of …
older adults. Increasing evidence suggests stroke contributes to the risk and severity of …
Age-related immune alterations and cerebrovascular inflammation
Aging is associated with chronic systemic inflammation, which contributes to the
development of many age-related diseases, including vascular disease. The world's …
development of many age-related diseases, including vascular disease. The world's …
Infection as a stroke risk factor and determinant of outcome after stroke
Understanding the relationship between infection and stroke has taken on new urgency in
the era of the coronavirus disease 2019 (COVID-19) pandemic. This association is not a …
the era of the coronavirus disease 2019 (COVID-19) pandemic. This association is not a …
Mechanical ventilation in patients with acute ischaemic stroke: from pathophysiology to clinical practice
Most patients with ischaemic stroke are managed on the ward or in specialty stroke units, but
a significant number requires higher-acuity care and, consequently, admission to the …
a significant number requires higher-acuity care and, consequently, admission to the …
New insights into the roles of microglial regulation in brain plasticity-dependent stroke recovery
F Yu, T Huang, Y Ran, D Li, L Ye, G Tian… - Frontiers in Cellular …, 2021 - frontiersin.org
Stroke remains the leading cause of long-term disability worldwide with significant long-term
sequelae. However, there is no highly effective treatment to enhance post-stroke recovery …
sequelae. However, there is no highly effective treatment to enhance post-stroke recovery …
[HTML][HTML] CD11bhigh B cells increase after stroke and regulate microglia
JM Korf, P Honarpisheh, EC Mohan… - The Journal of …, 2022 - journals.aai.org
Recent studies have highlighted the deleterious contributions of B cells to post-stroke
recovery and cognitive decline. Different B cell subsets have been proposed on the basis of …
recovery and cognitive decline. Different B cell subsets have been proposed on the basis of …
Transfer RNA fragments replace microRNA regulators of the cholinergic poststroke immune blockade
Stroke is a leading cause of death and disability. Recovery depends on a delicate balance
between inflammatory responses and immune suppression, tip** the scale between brain …
between inflammatory responses and immune suppression, tip** the scale between brain …