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Respiration-entrained brain rhythms are global but often overlooked
We revisit recent evidence showing that nasal respiration entrains oscillations at the same
frequency as breathing in several regions of the rodent brain. Moreover, respiration …
frequency as breathing in several regions of the rodent brain. Moreover, respiration …
Conundrums of high-frequency oscillations (80–800 Hz) in the epileptic brain
Pathological high-frequency oscillations (HFOs)(80–800 Hz) are considered biomarkers of
epileptogenic tissue, but the underlying complex neuronal events are not well understood …
epileptogenic tissue, but the underlying complex neuronal events are not well understood …
Heteromeric channels formed by TRPC 1, TRPC 4 and TRPC 5 define hippocampal synaptic transmission and working memory
J Bröker‐Lai, A Kollewe, B Schindeldecker… - The EMBO …, 2017 - embopress.org
Canonical transient receptor potential (TRPC) channels influence various neuronal
functions. Using quantitative high‐resolution mass spectrometry, we demonstrate that TRPC …
functions. Using quantitative high‐resolution mass spectrometry, we demonstrate that TRPC …
Impaired theta-gamma coupling in APP-deficient mice
Amyloid precursor protein (APP) is critically involved in the pathophysiology of Alzheimer's
disease, but its physiological functions remain elusive. Importantly, APP knockout (APP-KO) …
disease, but its physiological functions remain elusive. Importantly, APP knockout (APP-KO) …
Temporal relations between cortical network oscillations and breathing frequency during REM sleep
Nasal breathing generates a rhythmic signal which entrains cortical network oscillations in
widespread brain regions on a cycle-to-cycle time scale. It is unknown, however, how …
widespread brain regions on a cycle-to-cycle time scale. It is unknown, however, how …
[HTML][HTML] Diazepam effects on local cortical neural activity during sleep in mice
GABA-ergic neurotransmission plays a key role in sleep regulatory mechanisms and in brain
oscillations during sleep. Benzodiazepines such as diazepam are known to induce sedation …
oscillations during sleep. Benzodiazepines such as diazepam are known to induce sedation …
Theta-gamma coupling during REM sleep depends on breathing rate
Temporal coupling between theta and gamma oscillations is a hallmark activity pattern of
several cortical networks and becomes especially prominent during REM sleep. In a parallel …
several cortical networks and becomes especially prominent during REM sleep. In a parallel …
Sleep stage dynamics in neocortex and hippocampus
Mammalian sleep comprises the stages of slow-wave sleep (SWS) and rapid eye movement
(REM) sleep. Additionally, a transition state is often discriminated which in rodents is termed …
(REM) sleep. Additionally, a transition state is often discriminated which in rodents is termed …
The GABAA receptor modulator zolpidem augments hippocampal-prefrontal coupling during non-REM sleep
Abstract Benzodiazepines and 'Z-drugs'(including zolpidem and zopiclone) are GABAA
receptor (GABAAR) positive modulators commonly prescribed as hypnotics to treat insomnia …
receptor (GABAAR) positive modulators commonly prescribed as hypnotics to treat insomnia …
Pharmaco‐electroencephalographic responses in the rat differ between active and inactive locomotor states
IH Hansen, C Agerskov, L Arvastson… - European Journal of …, 2019 - Wiley Online Library
Quantitative electroencephalography from freely moving rats is commonly used as a
translational tool for predicting drug‐effects in humans. We hypothesized that drug‐effects …
translational tool for predicting drug‐effects in humans. We hypothesized that drug‐effects …